ChemicalBook--->CAS DataBase List--->134978-99-7

134978-99-7

134978-99-7 Structure

134978-99-7 Structure
IdentificationBack Directory
[Name]

Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
[CAS]

134978-99-7
[Synonyms]

134978-99-7
NH2-PEG3-CH2COOH
Amino-PEG3-CH2COOH
Amino-PEG3-CH2CO2H
AMINE-PEG3-CH2COOH
Amino-PEG3-CH2CO3H
2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]acetic acid
Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-
[Molecular Formula]

C8H17NO5
[MDL Number]

MFCD24479841
[MOL File]

134978-99-7.mol
[Molecular Weight]

207.22
Chemical PropertiesBack Directory
[Boiling point ]

360.3±27.0 °C(Predicted)
[density ]

1.164±0.06 g/cm3(Predicted)
[storage temp. ]

Store at Room Tem.
[form ]

Viscous Liquid
[pka]

3.39±0.10(Predicted)
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Polyethylene Glycol-->11-Azido-3,6,9-trioxaundecanoic Acid-->1-METHANESULFONYL-11-HYDROXY-3,6,9-TRIOXAUNDECANE-->Hydroxy-PEG3-Mes-->Tetraethylene glycol p-toluenesulfonate-->1-Azido-3,6,9-trioxaundecane-11-ol-->2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL-->2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL-->tetraethylene glycol-->Triethylene glycol
Hazard InformationBack Directory
[Uses]

Amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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