| Identification | Back Directory | [Name]
Biotin-PEG6-t-butyl ester | [CAS]
1352814-07-3 | [Synonyms]
Biotin-PEG6-Boc
Biontin-PEG6-Boc
Biotin-PEG6-t-butyl ester
4,7,10,13,16,19-Hexaoxa-22-azaheptacosanoic acid, 27-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-23-oxo-, 1,1-dimethylethyl ester | [Molecular Formula]
C29H53N3O10S | [MDL Number]
MFCD31693696 | [MOL File]
1352814-07-3.mol | [Molecular Weight]
635.81 |
| Hazard Information | Back Directory | [Description]
Biotin-PEG6-t-butyl ester is a PEG linker with a biotin and a t-butyl ester. The biotin group is used for the conjugation of proteins and can also be used for labeling. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | [Uses]
Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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