| Identification | Back Directory | [Name]
H2N-PEG12-tBu | [CAS]
1383814-00-3 | [Synonyms]
H2N-PEG12-tBu
Amino-PEG12-Boc
NH2-PEG12-CH2CH2COOtBu
Amino-PEG12-t-Bu Ester
AMINO-PEG12-PROPANOIC ACID T-BUTYL ESTER
tert-Butyl 1-amino-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate | [Molecular Formula]
C31H63NO14 | [MDL Number]
MFCD11041147 | [MOL File]
1383814-00-3.mol | [Molecular Weight]
673.83 |
| Chemical Properties | Back Directory | [Boiling point ]
665.0±50.0 °C(Predicted) | [density ]
1.080±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C, protect from light | [form ]
Liquid | [pka]
8.74±0.10(Predicted) | [color ]
Colorless to light yellow | [InChIKey]
XRYCYKGEIYZQGE-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
| Hazard Information | Back Directory | [Uses]
Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [General Description]
H2N-PEG12-tBu (CAS 1383814-00-3) is a high-purity polyethylene glycol (PEG) linker. Its synonyms include Amino-PEG12-Boc, Amino-PEG12-t-butyl ester, H₂N-PEG12-CH₂CH₂COO-tBu and NH₂-PEG12-CH₂CH₂COO-tBu,
among others. This compound is characterised by its hydrophilic PEG backbone, which enhances the solubility and stability of therapeutic drugs, and is widely used in the field of biochemical research. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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