ChemicalBook--->CAS DataBase List--->14432-12-3

14432-12-3

14432-12-3 Structure

14432-12-3 Structure
IdentificationMore
[Name]

4-Amino-2-chloropyridine
[CAS]

14432-12-3
[Synonyms]

2-CHLORO-4-AMINOPYRIDINE
2-CHLORO-4-PYRIDINAMINE
2-CHLOROPYRIDIN-4-AMINE
2-CHLORO-PYRIDIN-4-YLAMINE
4-AMINO-2-CHLOROPYRIDINE
TIMTEC-BB SBB004235
4-Pyridinamine, 2-chloro-
2-CHLORO-4-AMINOPYRIDINE 97%
AMINO-2-CHLOROPYRIDINE, 4-
2-CHLORO-4-AMINOPVRIDINE
4-Pyridinamine,2-chloro-(9CI)
4-Amino-2-Chloropyridine 98.5%
2-Chloro-4-aminopyridine ,99%
2-Chloro-4-aminopyri
[EINECS(EC#)]

238-403-0
[Molecular Formula]

C5H5ClN2
[MDL Number]

MFCD00060089
[Molecular Weight]

128.56
[MOL File]

14432-12-3.mol
Chemical PropertiesBack Directory
[Appearance]

White powder.
[Melting point ]

90-94 °C(lit.)
[Boiling point ]

153°C 5mm
[density ]

1.2417 (rough estimate)
[refractive index ]

1.5110 (estimate)
[Fp ]

153°C/5mm
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Crystalline Powder
[pka]

4.73±0.30(Predicted)
[color ]

Light yellow
[Water Solubility ]

Slightly soluble in water.
[Detection Methods]

HPLC
[BRN ]

108671
[InChI]

1S/C5H5ClN2/c6-5-3-4(7)1-2-8-5/h1-3H,(H2,7,8)
[InChIKey]

BLBDTBCGPHPIJK-UHFFFAOYSA-N
[SMILES]

Nc1ccnc(Cl)c1
[CAS DataBase Reference]

14432-12-3(CAS DataBase Reference)
[NIST Chemistry Reference]

4-Amino-2-chloropyridine(14432-12-3)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
[RIDADR ]

2811
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HazardClass ]

IRRITANT
[HS Code ]

29333990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Nitric acid-->2-Chloro-4-pyridinecarboxylic acid-->Isonicotinic acid-->2-Chloropyridine-N-oxide-->4-Pyridinecarbonyl azide, 2-chloro--->2-Chloro-4-nitropyridine-->4-Nitropyridine N-oxide-->2,4-Dihydroxypyridine
[Preparation Products]

2-Chloro-pyridine-3,4-diamine-->2-Chloro-4,5-diaminopyridine hydrochloride-->Forchlorfenuron-->6-Chloro-3,4-pyridinediamine-->4-Amino-2-chloro-3-nitropyridine-->2-Chloro-5-nitropyridin-4-amine-->2-Chloro-4-bromopyridine-->4-Acetamido-2-chloropyridine-->2-Chloropyridine-4-sulfonyl chloride-->2-Chloro-4-hydroxypyridine-->4-Amino-3-bromo-2-methoxypyridine-->4-Fluoro-2-methoxypyridine
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Chloro-4-pyridinamine(14432-12-3).msds
Questions And AnswerBack Directory
[Description]

4-Amino-2-chloropyridine is an important pharmaceutical and pesticide intermediate. It can synthesize N-(2-chloro-4-pyridyl)urea regulators that promote plant growth. It is also a key substance in the synthesis of KT-30 (Forchlorfenuron, IUPAC name N-(2-chloro-4-pyridyl)-N'-phenylurea). KT-30 is a highly active cytokinin, which has the biological activity of promoting tissue growth, promoting bud development and green preservation; it has an effect of increasing yield on apple, pear, grape, peach and other fruit crops.
4-Amino-2-chloropyridine itself can also be used as a pesticide alone, and has high activity against various pathogens such as rust, powdery mildew, rice blast, and apple downy mildew. 4-Amino-2-chloropyridine and its pharmaceutical and pesticide intermediates have the advantages of high biological activity, low toxicity, long-lasting period and easy degradation in the environment, so they have broad application prospects in agricultural production.

Hazard InformationBack Directory
[Chemical Properties]

White powder.
[Uses]

An aminopyridine derivative with potential herbicidal activity.
[Definition]

ChEBI:4-Amino-2-chloropyridine is an aminopyridine.
[Reactions]

4-amino-2-chloropyridine (3 b) can be used as starting compound in the synthesis of novel cyclin-dependent kinase (CDK2) inhibitors and high-energy compounds.[1]
[General Description]

4-Amino-2-chloropyridine is a chloroaminoheterocyclic compound. It readily undergoes Suzuki-Miyaura coupling with phenylboronic acid.
[References]

[1] Dinitropyridines: Synthesis and Reactions. Asian J. Org. Chem. 2024, e202400304. DOI:10.1002/ajoc.202400304
Spectrum DetailBack Directory
[Spectrum Detail]

4-Amino-2-chloropyridine(14432-12-3)MS
4-Amino-2-chloropyridine(14432-12-3)1HNMR
4-Amino-2-chloropyridine(14432-12-3)IR1
4-Amino-2-chloropyridine(14432-12-3)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Amino-2-chloropyridine, 97%(14432-12-3)
[Alfa Aesar]

4-Amino-2-chloropyridine, 98%(14432-12-3)
[Sigma Aldrich]

14432-12-3(sigmaaldrich)
[TCI AMERICA]

4-Amino-2-chloropyridine,>98.0%(T)(14432-12-3)
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