| Identification | Back Directory | [Name]
RuPhos Pd G3 | [CAS]
1445085-77-7 | [Synonyms]
RuPhos Pd G3
RuPhos-Pd-G3
RuPhos Pd G3 95%
RuPhos-G3-Palladacycle
Methanesulfonato(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)
(2-Dicyclohexylphosphino-2′,6′-diisopropoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate
Methanesulfonato(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl)palladiuM(II), Min. 98%
Methanesulfonato(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) OMS-RuPhos
[2'-(Amino)[1,1'-biphenyl]-2-yl][[2',6'-bis(1-methylethoxy)[1,1'-biphenyl]-2-yl]dicyclohexylphosphine](methanesulfonato)palladium
[2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC][[2',6'-bis(1-methylethoxy)[1,1'-biphenyl]-2-yl]dicyclohexylphosphine-κP](methanesulfonato-κO)palladium
Methanesulfonato(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl)palladiuM(II), Min. 98% [RuPhos Palladacycle]
Methanesulfonato(2-dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), min. 98% [RuPhos Palladacycle Gen. 3] | [Molecular Formula]
C43H56NO5PPdS | [MDL Number]
MFCD22572684 | [MOL File]
1445085-77-7.mol | [Molecular Weight]
837.375 |
| Questions And Answer | Back Directory | [Synthesis]
mixture of μ-OMs dimer Et₂O (a 1:1 complex characterized by 1H NMR) (0.5 equivalents, 0.871 g, 1.071 mmol), 1,1'-(diphenylphosphino)ferrocene (1.0 equivalents, 1.2 g, 2.141 mmol), and anhydrous THF (15.0 mL) was stirred at room temperature under an argon atmosphere for 1 hour. The solvent was removed under vacuum. The crude product was treated with n-pentane (75.0 mL) as a triurate. The resulting mixture was dried under vacuum for 24 hours to give the product RuPhos Pd G3.
 Figure: Synthetic route of RuPhos Pd G3"> Synthetic route of RuPhos Pd G3 | [Reaction]
- Palladium catalyst used for facile, C-N cross-coupling reactions.
- A practical synthesis of indoles via a Pd-catalyzed C-N ring formation.
|
| Chemical Properties | Back Directory | [Melting point ]
188-196°C (decomposition) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Powder | [color ]
white | [InChI]
InChI=1S/C30H43O2P.C12H10N.CH4O3S.Pd/c1-22(2)31-27-19-13-20-28(32-23(3)4)30(27)26-18-11-12-21-29(26)33(24-14-7-5-8-15-24)25-16-9-6-10-17-25;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h11-13,18-25H,5-10,14-17H2,1-4H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;-1;; | [InChIKey]
GYTUQNMMIUJBSP-UHFFFAOYSA-N | [SMILES]
[Pd].S(C([H])([H])[H])(=O)(=O)O[H].P(C1=C([H])C([H])=C([H])C([H])=C1C1C(=C([H])C([H])=C([H])C=1OC([H])(C([H])([H])[H])C([H])([H])[H])OC([H])(C([H])([H])[H])C([H])([H])[H])(C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H].N([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=[C-]1 | [CAS DataBase Reference]
1445085-77-7 |
| Hazard Information | Back Directory | [Uses]
RuPhos Pd G3 can be used as a pre-catalyst in the following protocols:
- Palladium-catalyzed Suzuki coupling of 5-p-toluenesulfonyltetrazoles with arylboronic acids to synthesize 1,5-disubstituted tetrazoles.
- Suzuki-Miyaura catalyst-transfer polycondensation (SCTP) of 3-alkylthiophenes in the presence of N-methylimidodiacetic (MIDA)-boronate monomers.
- Suzuki-Miyaura-cross-coupling of aminothiophenes.
| [General Description]
RuPhos Pd G3 is a third generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. It is air-, moisture-, and thermally-stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio. | [reaction suitability]
reagent type: catalyst
reaction type: Cross Couplings |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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Jia Xing Isenchem Co.,Ltd
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