| Identification | More | [Name]
4'-Fluoro-2'-hydroxyacetophenone | [CAS]
1481-27-2 | [Synonyms]
4'-FLUORO-2'-HYDROXYACETOPHENONE
4-FLUORO-2-HYDROXYACETOPHENONE
4-Fluoro-2-hydroxyacethophenone, 98%
4'-Fluoro-2'-hydroxyacetophenone 98%
4'-Fluoro-2'-hydroxyacetophenone98%
4'-fluoro-2'-hydroxyacetophenone,1-(4-fluoro-2-hydroxyphenyl)ethanone
1-(4-fluoro-2-hydroxyphenyl)ethanone | [Molecular Formula]
C8H7FO2 | [MDL Number]
MFCD00143203 | [Molecular Weight]
154.14 | [MOL File]
1481-27-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29147000 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to yellow liquid | [Uses]
4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate. | [Preparation]
Preparation by Fries rearrangement of 3-fluorophenyl acetate with aluminium chloride without solvent at 160–180° (75%) (88–90%). | [General Description]
4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n. |
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