| Identification | More | [Name]
Cloperastine hydrochloride | [CAS]
14984-68-0 | [Synonyms]
1-[2-[(4-chlorophenyl)phenylmethoxy]ethyl]piperidinium chloride
4-CHLOROBENZHYDRYL 2-[1-PIPERIDYL]-ETHYL ETHER HYDROCHLORIDE
CHLOPERASTINE HYDROCHLORIDE
CLOPERASTINE HCL
CLOPERASTINE HYDROCHLORIDE
1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidinehydrochloride
1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)-piperidinhydrochloride
1-(2-(p-cloro-alpha-fenilbenzilossi)etil)piperidinacloridrato
2-piperidinoethylp-chlorobenzhydryletherhydrochloride
cloperastinacloridrato
ht11
hustazol
4-chlorobenzhydryl 2-(1-piperidyl)ethyl ether | [EINECS(EC#)]
239-067-8 | [Molecular Formula]
C20H25Cl2NO | [MDL Number]
MFCD00079012 | [Molecular Weight]
366.32 | [MOL File]
14984-68-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
147.9° | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
White to Off-White | [Merck ]
14,2395 | [Major Application]
forensics and toxicology
pharmaceutical (small molecule)
veterinary | [InChI]
InChI=1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H | [InChIKey]
UNPLRYRWJLTVAE-UHFFFAOYSA-N | [SMILES]
C(OCCN1CCCCC1)(C1C=CC=CC=1)C1=CC=C(Cl)C=C1.Cl | [CAS DataBase Reference]
14984-68-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
TM6491500
| [HS Code ]
2933.39.9200 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
Antitussive;'Histamine antagonist | [Definition]
ChEBI: Cloperastine hydrochloride is a diarylmethane. | [in vivo]
In the anesthetized guinea pigs, Cloperastine at a therapeutic dose of 1 mg/kg prolonged the QT interval and monophasic?
action potential (MAP) duration without affecting PR interval or QRS width[1].
?
Cloperastine hydrochloride shows relatively low acute toxicity when administered by the intraperitoneal route in rats and mice, and shows minor toxicity by the oral route when administered as Cloperastine fendizoate, the LD50 in rats and mice for the two administration routes exceeds 1000 and 2000 mg/kg, respectively[2]. |
|
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|