ChemicalBook--->CAS DataBase List--->179344-98-0

179344-98-0

179344-98-0 Structure

179344-98-0 Structure
IdentificationBack Directory
[Name]

V-PYRRO/NO
[CAS]

179344-98-0
[Synonyms]

V-PYRRO/NO
PYRRO NONOATE
1-[(ETHENYLOXY)-NNO-AZOXY]-PYRROLIDINE
V-PYRRO/NO, 1-[(ethenyloxy)-NNO-azoxy]-pyrrolidine
O2-VINYL 1-(PYRROLIDIN-1-YL)DIAZEN-1-IUM-1,2-DIOLATE
O2-VINYL 1-(PYRROLIDIN-1-YL)DIAZEN-1-UIM-1,2-DIOLATE
1-(Ethenyloxy)-3-(2-pyrrolidinyl)-3-(5-pyrrolidinyl)-
1-(Ethenyloxy)-3-(2-pyrrolidinyl)-3-(5-pyrrolidinyl)-1-triazenamine 2-oxide
1-[(Ethenyloxy)-NNO-azoxy]-pyrrolidine, O2-Vinyl-1-(pyrrolidin-1-yl)diazen-1-uim-1,2-diolate
[Molecular Formula]

C6H11N3O2
[MDL Number]

MFCD06407925
[MOL File]

179344-98-0.mol
[Molecular Weight]

157.17
Chemical PropertiesBack Directory
[Appearance]

Pale Yellow Oil
[Boiling point ]

220.2±23.0 °C(Predicted)
[density ]

1.21±0.1 g/cm3(Predicted)
[Fp ]

14 °C
[storage temp. ]

−20°C
[solubility ]

Ethanol
[form ]

Pale yellow oil.
[color ]

Pale Yellow
[Stability:]

Store in Freezer (> 1 year at -20°)
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Oil
[Uses]

V-PYRRO/NO is a metabolically activated nitric oxide (NO) donor drug that can be used to selectively target NO delivery to the liver. The compound is metabolized by the liver, and spontaneously decom poses with a half-life of 3 seconds, liberating NO. Infusion of 30nmol/kg of V-PYRRO/NO in rats causes only a slight drop in blood pressure. At concentrations >100ug, V-PYRRO/NO increases hepatocyte viability against TNF-a-induced apoptosis by approximately 2-fold compared to cells not treated with this compound.
Safety DataBack Directory
[Hazard Codes ]

F
[Risk Statements ]

11
[Safety Statements ]

7-16
[RIDADR ]

UN 1170 3/PG 2
[WGK Germany ]

1
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