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1807503-88-3

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1807503-88-3 Structure

1807503-88-3 Structure
IdentificationBack Directory
[Name]

THP-SS-PEG1-t-butyl ester
[CAS]

1807503-88-3
[Synonyms]

THP-SS-PEG1-Boc
THP-SS-PEG1-t-butyl ester
[Molecular Formula]

C16H30O5S2
[MDL Number]

MFCD28505560
[MOL File]

1807503-88-3.mol
[Molecular Weight]

366.54
Chemical PropertiesBack Directory
[Boiling point ]

470.0±45.0 °C(Predicted)
[density ]

1.13±0.1 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
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