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1821-52-9

1821-52-9 Structure

1821-52-9 Structure
IdentificationMore
[Name]

DL-INDOLE-3-LACTIC ACID
[CAS]

1821-52-9
[Synonyms]

Indolelacticacid
indole-3-lacticacid
3-INDOLE-LACTIC ACID
DL-3-INDOLELACTIC ACID
Indole-3-lacticAcid>
3-(indol-3-yl)lacticaci
DL-INDOLE-3-LACTIC ACID
DL-B-3-INDOLELACTIC ACID
3-(3-INDOLYL)LACTIC ACID
ω-(3-Indolyl)lactic acid
3-(indol-3-yl)lactic acid
DL-3-(3-INDOLYL)-LACTIC ACID
DL-INDOLE-3-LACTIC ACID(ILA)
3-INDOLE-LACTIC ACID (BETA-) 99+%
α-Hydroxy-1H-indole-3-propanoic acid
α-Hydroxy-1H-indole-3-propionic acid
3-[3-INDOLYL]-2-HYDROXYPROPANOIC ACID
2-hydroxy-3-(1H-indol-3-yl)propanoate
2-Hydroxy-3-(3-indolyl)propionic Acid
1H-Indole-3-propanoic acid, α-hydroxy-
2-Hydroxy-3-(1H-indole-3-yl)propionic acid
2-hydroxy-3-(1H-indol-3-yl)-propionic acid
1H-Indole-3-propanoic acid, alpha-hydroxy-
3-indole-lactic acid , (DL-INDOLE-3-LACTIC ACID)
3-(3-Indolyl)lactic Acid 2-Hydroxy-3-(3-indolyl)propionic Acid
[EINECS(EC#)]

217-347-0
[Molecular Formula]

C11H11NO3
[MDL Number]

MFCD00005642
[Molecular Weight]

205.21
[MOL File]

1821-52-9.mol
Chemical PropertiesBack Directory
[Melting point ]

145-146 °C(lit.)
[Boiling point ]

477.3±30.0 °C(Predicted)
[density ]

1.428±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

3.86±0.11(Predicted)
[color ]

Pale Orange to Pale Purple
[InChI]

InChI=1S/C11H11NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,10,12-13H,5H2,(H,14,15)
[InChIKey]

XGILAAMKEQUXLS-UHFFFAOYSA-N
[SMILES]

C(O)(=O)C(O)CC1C2=C(NC=1)C=CC=C2
[CAS DataBase Reference]

1821-52-9(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)Flame (GHS02)
GHS07,GHS08,GHS02
[Signal word ]

Danger
[Hazard statements ]

H319-H360-H372-H373-H340-H335-H336-H401-H225
[Precautionary statements ]

P501-P273-P260-P270-P202-P240-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P308+P313-P337+P313-P305+P351+P338-P303+P361+P353-P304+P340+P312-P403+P233-P403+P235-P405
[WGK Germany ]

3
[HS Code ]

2933.99.9701
Hazard InformationBack Directory
[Uses]

DL-Indole-3-lactic Acid is used as a reagent in the synthesis of 2-hydroxy-1-(1H-indol-3-yl)-4-methylpentan-3-one which has weak antibacterial activity against 16 bacterial strains, including Escherichia coli, Bacillus subtilis and Staphylococcus aureus. DL-Indole-3-lactic Acid is also used in the preparation of Monatin, a natural sweet peptidomimetic.
[Definition]

ChEBI: A hydroxy monocarboxylic acid that is lactic acid substituted by a 1H-indol-3-yl group at position 3. It is a metabolite of tryptophan.
[in vivo]

Indolelactic acid (gavage feeding, 10 μM, 5 μL, 5 days, C57BL/6 mice) benefits the immature intestine preferentially[4].

Animal Model:C57BL/6 mice[4]
Dosage:10 μM, 5 μL
Administration:Gavage feeding, 5 days
Result:Upregulated the innate immune response genes in immature mouse intestine (C57-pup-ileum), with no effects on pup-colon or adult intestine.
[IC 50]

Human Endogenous Metabolite
[storage]

Store at 2-8°C
Spectrum DetailBack Directory
[Spectrum Detail]

DL-INDOLE-3-LACTIC ACID(1821-52-9)MS
DL-INDOLE-3-LACTIC ACID(1821-52-9)1HNMR
DL-INDOLE-3-LACTIC ACID(1821-52-9)IR1
DL-INDOLE-3-LACTIC ACID(1821-52-9)IR2
Well-known Reagent Company Product InformationBack Directory
[TCI AMERICA]

3-Indole-lactic Acid,>98.0%(LC)(T)(1821-52-9)
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