ChemicalBook--->CAS DataBase List--->192182-56-2

192182-56-2

192182-56-2 Structure

192182-56-2 Structure
IdentificationMore
[Name]

4-Isoquinolineboronic acid
[CAS]

192182-56-2
[Synonyms]

4-ISOQUINOLINEBORONIC ACID
4-ISOQUINOLINYLBORONI ACID
5-ISOQUINOLINEBORONIC ACID
AKOS BRN-0121
AKOS BRN-0458
CHEMBRDG-BB 4002849
ISOQUINOLIN-4-YLBORONIC ACID
ISOQUINOLIN-5-YLBORONIC ACID
ISOQUINOLINE-4-BORONIC ACID
ISOQUINOLINE-5-BORONIC ACID
RARECHEM AK VD 0025
RARECHEM AK VD 0026
ISOQUINOLYL-4-YL-BORONIC ACID
Isoquinoline-4-boronic acid, 2,2-dimethylpropane-1,3-diol cyclic ester
4-Isoquinolinylboronic acid
[Molecular Formula]

C9H8BNO2
[MDL Number]

MFCD03839356
[Molecular Weight]

172.98
[MOL File]

192182-56-2.mol
Chemical PropertiesBack Directory
[Melting point ]

178°C
[Boiling point ]

419.1±37.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

4.61±0.30(Predicted)
[Detection Methods]

HPLC
[CAS DataBase Reference]

192182-56-2(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[Hazard Note ]

Irritant
[HazardClass ]

IRRITANT
[HS Code ]

29349990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Diethyl ether-->Tetrahydrofuran-->Government regulation-->n-Butyllithium-->Nitrogen-->Hydrogen bromide-->Triisopropyl borate-->Isoquinoline-->4-Bromoisoquinoline
[Preparation Products]

4-NITROISOQUINOLINE
Hazard InformationBack Directory
[Chemical Properties]

Pink solid
[Uses]

Reactant for:
  • Preparation of selective steroid-11β-hydroxylase (CYP11B1) inhibitors for treatment of cortisol dependent diseases
  • Preparation of tetrabutylammonium trifluoroborates
  • Preparation of heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors
  • Synthesis of aminoarylpyridazines as selective CB2 agonists for treatment of inflammatory pain
  • Preparation of acyl substituted indoles via palladium-catalyzed domino coupling/carbonylation/Suzuki coupling of dibromoethenylanilines
  • Synthesis of antagonists of bacterial quorum sensing
  • Preparation of potassium heteroaryl trifluoroborates from boronic acids and their use as coupling partners with various aryl and heteroaryl halides in Suzuki-Miyaura cross-coupling reactions
[General Description]

May contain varying amounts of anhydride
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Isoquinoline-4-boronic acid, 97%(192182-56-2)
[Sigma Aldrich]

192182-56-2(sigmaaldrich)
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