| Identification | More | [Name]
2-Amino-4-phenylthiazole | [CAS]
2010-06-2 | [Synonyms]
2-AMINO-4-PHENYLTHIAZOLE
4-PHENYL-1,3-THIAZOL-2-AMINE
4-PHENYL-THIAZOL-2-YLAMINE
AKOS B000316
AKOS BBS-00004476
AKOS BC-0800
ASISCHEM T31190
AURORA 5314
BUTTPARK 41\09-31
IFLAB-BB F1386-0378
OTAVA-BB BB0108540041
TIMTEC-BB SBB003778
TOSLAB 3052
2-amino-4-phenyl-thiazol
4-Phenyl-2-aminothiazole
4-phenyl-2-thiazolamin
4-Phenyl-2-thiazolamine
4-Phenyl-2-thiazolylamine
Thiazole, 2-amino-4-phenyl-
4-phenylthiazol-2-amine | [EINECS(EC#)]
217-926-8 | [Molecular Formula]
C9H8N2S | [MDL Number]
MFCD00039680 | [Molecular Weight]
176.24 | [MOL File]
2010-06-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
149-153 °C (lit.) | [Boiling point ]
363.4±11.0 °C(Predicted) | [density ]
1.261±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml | [form ]
Crystalline Solid | [pka]
4.33±0.10(Predicted) | [color ]
White to yellow to pale orange | [λmax]
284nm(EtOH)(lit.) | [BRN ]
128609 | [InChI]
1S/C9H8N2S/c10-9-11-8(6-12-9)7-4-2-1-3-5-7/h1-6H,(H2,10,11) | [InChIKey]
PYSJLPAOBIGQPK-UHFFFAOYSA-N | [SMILES]
Nc1nc(cs1)-c2ccccc2 | [CAS DataBase Reference]
2010-06-2(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Thiazolamine, 4-phenyl-(2010-06-2) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3
| [RTECS ]
XJ2878000
| [HazardClass ]
6.1 | [HazardClass ]
IRRITANT | [PackingGroup ]
III | [HS Code ]
29341000 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 | [Toxicity]
mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00815, |
| Hazard Information | Back Directory | [Description]
2-amino-4-phenyl Thiazole is a synthetic intermediate useful for pharmaceutical synthesis. | [Uses]
4-Phenyl-2-thiazolamine was used to prepare suberoylanilide hydroxamic acid (SAHA) analogs with cancer cell growth inhibitory activities. It was also used to synthesize ketone histone deacetylase inhibitors with antitumor activity in vivo. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|