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20183-47-5

20183-47-5 Structure

20183-47-5 Structure
IdentificationBack Directory
[Name]

2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
[CAS]

20183-47-5
[Synonyms]

Tenuifolin
Tenuifoline
Tenuifolin, >=98%
Tenuifolin Impurity 1
Tenuifolin, 98%, from Polygala tenuifolia Willd.
2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
3β-(β-D-Glucopyranosyloxy)-2β,27-dihydroxyoleana-12-ene-23,28-dioic acid
(4S)-3β-(β-D-Glucopyranosyloxy)-2β,27-dihydroxyolean-12-ene-23,28-dioic acid
(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid
2beta,27-Dihydroxy-3beta-(beta-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β,4α)-
(2beta,3beta)-3-(beta-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic Acid
[Molecular Formula]

C36H56O12
[MDL Number]

MFCD32004655
[MOL File]

20183-47-5.mol
[Molecular Weight]

680.83
Chemical PropertiesBack Directory
[Melting point ]

201-204℃
[Boiling point ]

853.6±65.0 °C(Predicted)
[density ]

1.39
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
[form ]

Solid
[pka]

4.15±0.70(Predicted)
[color ]

White to Off-White
[Water Solubility ]

slightly soluble in water
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Safety Statements ]

24/25
[HS Code ]

29389090
Hazard InformationBack Directory
[Uses]

Tenuifolin is a terpenoid with potential to treat Alzheimer’s disease.
[in vivo]

Tenuifolin (20-80 mg/kg; po; single dose) induces beneficial effects on learning and memory, prevents loss and apoptosis of neurons in APP/PS1 mice[2].

[IC 50]

AChE
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