| Identification | Back Directory | [Name]
2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid | [CAS]
20183-47-5 | [Synonyms]
Tenuifolin
Tenuifoline
Tenuifolin, >=98%
Tenuifolin Impurity 1
Tenuifolin, 98%, from Polygala tenuifolia Willd.
2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
3β-(β-D-Glucopyranosyloxy)-2β,27-dihydroxyoleana-12-ene-23,28-dioic acid
(4S)-3β-(β-D-Glucopyranosyloxy)-2β,27-dihydroxyolean-12-ene-23,28-dioic acid
(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid
2beta,27-Dihydroxy-3beta-(beta-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β,4α)-
(2beta,3beta)-3-(beta-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic Acid | [Molecular Formula]
C36H56O12 | [MDL Number]
MFCD32004655 | [MOL File]
20183-47-5.mol | [Molecular Weight]
680.83 |
| Chemical Properties | Back Directory | [Melting point ]
201-204℃ | [Boiling point ]
853.6±65.0 °C(Predicted) | [density ]
1.39 | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) | [form ]
Solid | [pka]
4.15±0.70(Predicted) | [color ]
White to Off-White | [Water Solubility ]
slightly soluble in water | [Stability:]
Hygroscopic | [Major Application]
food and beverages | [InChIKey]
DBJLNNAUDGIUAE-YRAPYSFMNA-N | [SMILES]
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OC2[C@@](C3[C@@](C4[C@]([C@@]5(CCC6(C(CC(CC6)(C)C)C5=CC4)C(=O)O)CO)(CC3)C)(CC2O)C)(C)C(=O)O |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, derived from Polygala tenuifolia. | [Uses]
Tenuifolin is a terpenoid with potential to treat Alzheimer’s disease. | [in vivo]
Tenuifolin (20-80 mg/kg; po; single dose) induces beneficial effects on learning and memory, prevents loss and apoptosis of neurons in APP/PS1 mice[2].
| [IC 50]
AChE |
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