| Identification | More | [Name]
Amyl salicylate | [CAS]
2050-08-0 | [Synonyms]
AMYL SALICYLATE
N-AMYL SALICYLATE
PENTYL-2-HYDROXYBENZOATE
PENTYL SALICYLATE
2-hydroxy-benzoicacipentylester
Amylester kyseliny salicylove
amylesterkyselinysalicylove
Benzoic acid, 2-hydroxy-, pentyl ester
Benzoicacid,2-hydroxy-,pentylester
Pentyl-o-hydroxybenzoate
Salicylic acid, amyl ester
Salicylic acid, pentyl ester
salicylicacid,pentylester
salicylicacidpentylester
OXY AMYL SALICYLATE
n-Amyl-2-hydroxybenzoate
Pentylsalicylat
2-Hydroxybenzoic acid pentyl ester
Amylenol
Salicylic acid amyl | [EINECS(EC#)]
218-080-2 | [Molecular Formula]
C12H16O3 | [MDL Number]
MFCD00082813 | [Molecular Weight]
208.25 | [MOL File]
2050-08-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
-12° | [Boiling point ]
270°C | [density ]
1.056 | [vapor pressure ]
0.24Pa at 20℃ | [FEMA ]
2084 | [refractive index ]
1.512 | [Fp ]
>93.3° | [storage temp. ]
-20°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Oil | [pka]
8.16±0.30(Predicted) | [color ]
Colourless | [Odor]
at 100.00 %. herbal floral clover azalea green sweet chocolate | [Odor Type]
floral | [Water Solubility ]
5.5mg/L at 20℃ | [BRN ]
2577253 | [Major Application]
cleaning products
cosmetics
food and beverages
personal care | [Cosmetics Ingredients Functions]
SKIN CONDITIONING
PERFUMING | [InChI]
1S/C12H16O3/c1-2-3-6-9-15-12(14)10-7-4-5-8-11(10)13/h4-5,7-8,13H,2-3,6,9H2,1H3 | [InChIKey]
RANVDUNFZBMTBK-UHFFFAOYSA-N | [SMILES]
O=C(OCCCCC)C1=CC=CC=C1O | [LogP]
4.4 | [CAS DataBase Reference]
2050-08-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzoic acid, 2-hydroxy-, pentyl ester(2050-08-0) | [EPA Substance Registry System]
2050-08-0(EPA Substance) |
| Safety Data | Back Directory | [RIDADR ]
UN 3082 9 / PGIII | [WGK Germany ]
WGK 2 | [RTECS ]
VO5425000 | [TSCA ]
TSCA listed | [HazardClass ]
9 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Chemical Properties]
Amyl salicylate, also called isoamyl salicylate, is a colourless, transparent liquid with a delicate floral fragrance. It is insoluble in water but readily soluble in organic solvents, including diethyl ether, acetic acid, ethanol, acetone, benzene, and carbon tetrachloride. | [Occurrence]
Apparently has not been reported to occur in nature. | [Uses]
cleaning products
cosmetics
food and beverages
personal care | [Definition]
ChEBI: Amyl salicylate is a benzoate ester. | [Preparation]
By esterification of salicylic acid with the isomeric amyl alcohols obtained from fusel oil and other sources. | [Toxicity evaluation]
The LD50 value iv in dogs was reported as 0.5-0.8 g/kg(Fassett, 1963).Human testing. A maximization test(Kligman, 1966) was carried out on 25 volunteers. The material was tested at a concentration of 10% in petrolatum and produced no reactions(Kligman, 1970).Aspirin-containing drugs will cause exacerbation in some patients with chronic urticaria. The action is probably due to the salicylate radical. It is suggested that aspirin acts in chronic urticaria by enhancing the effect of histamine in the skin(Moore-
Robinson & Warin, 1967). | [Metabolism]
Most of the esters of salicylic acid are decomposed to salicylic acid in the body and excreted as such. Besides the unchanged acid, salicuric acid, genticic acid and salicyl glucuronide have been known to be excreted. The lower esters of salicylic acid decompose more readily than the higher esters and as a consequence, little of the amyl ester is split. The whole subject of salicylic esters is covered in an extensive literature by Gross & Greenberg(1948). |
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