| Identification | Back Directory | [Name]
Clothianidin | [CAS]
210880-92-5 | [Synonyms]
Apacz
Belay
Clutch
Dantop
Poncho
TI 435
Celero
Pancho
Dantotsu
Fullswing
Hsdb 7281
Poncho 600
Ccris 9264
Poncho 250
Clothianidi
lothianidin
CLOTHIANIDIN
clothianidine
Chlothianidin
Clothianidin 0
Clothianidin [iso]
Clothianidin PESTANAL
CLOTHIANIDIN STANDARD
Clothianidin D3 (N'-methyl D3)
Clothianidin Reference Material
Clothianidin 100mg [210880-92-5]
Clothianidin@100 μg/mL in Methanol
Clothianidin@1000 μg/mL in Acetonitrile
2-(2-broMophenyl)-3a,7a-dihydro-1H-benzo[d]iMidazole
(E)-1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine
3-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-1-nitro-guanidine
(E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
(E)-N-[(2-Chloro-5-thiazolyl)Methyl]-N'-Methyl-N''-nitroguanidine
(E)-1-(2-Chloro-1,3-thiazole-5-ylMethyl)-3-Methyl-2-nitroguanidine
Guanidine, N-(2-chloro-5-thiazolyl)methyl-N-methyl-N-nitro-, C(E)- | [EINECS(EC#)]
205-516-1 | [Molecular Formula]
C6H8ClN5O2S | [MDL Number]
MFCD06200753 | [MOL File]
210880-92-5.mol | [Molecular Weight]
249.68 |
| Chemical Properties | Back Directory | [Melting point ]
178.8 °C | [Boiling point ]
412.5±55.0 °C(Predicted) | [density ]
1.61 | [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
0-6°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml | [form ]
neat | [pka]
2.76±0.50(Predicted) | [color ]
Off-white to light yellow | [Water Solubility ]
327 mg/L at 20 ºC | [Henry's Law Constant]
3.4×1010 mol/(m3Pa) at 25℃, MacBean (2012) | [Major Application]
agriculture
environmental | [InChI]
1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) | [InChIKey]
PGOOBECODWQEAB-UHFFFAOYSA-N | [SMILES]
CN\C(NCc1cnc(Cl)s1)=N/[N+]([O-])=O | [LogP]
0.7 at 25℃ | [CAS DataBase Reference]
210880-92-5 | [EPA Substance Registry System]
Clothianidin (210880-92-5) |
| Hazard Information | Back Directory | [Uses]
Insecticide. | [Description]
Clothianidin is an insecticide for the control of sucking and chewing pests. It is moderately soluble and volatile but has a high potential for leaching to groundwater. It is very persistent in soil and water. Risk of bioaccumulation is low and its acute toxicity to mammals is considered moderate. It is, however, a neurotoxicant. It is toxic to some aquatic organisms but not greatly so to fish. It is highly toxic to honeybees but low risk to earthworms. | [Definition]
ChEBI: (E)-clothianidin is a clothiadin that has E configuration at the C=N bond of the nitroguanidine moiety. It has a role as a neonicotinoid insectide. | [Production Methods]
The commercial production of clothianidin involves a multi-step chemical synthesis process designed for efficiency and scalability. It begins with a condensation reaction between 2-chloro-5-chloromethylthiazole and 1,5-dimethyl-2-nitroimino-hexahydro-1,3,5-triazine in an aqueous solution of tetraalkyl ammonium hydroxide, with potassium carbonate as a base. This reaction yields an intermediate compound, which is then subjected to hydrolysis in an alkylamine solution. The resulting product is purified through filtration, desolvation, extraction, and concentration steps to obtain clothianidin in its final form. | [Flammability and Explosibility]
Notclassified | [Mechanism of action]
Translaminar and root systemic activity. Nicotinic acetylcholine receptor (nAChR) channel blocker. | [storage]
Store at -20°C | [Pesticide Type]
Insecticide; Metabolite |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS07,GHS09 | [Signal word ]
Warning | [Hazard statements ]
H302-H410 | [Precautionary statements ]
P273-P301+P312+P330 | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-50/53 | [Safety Statements ]
46-60-61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
1 | [RTECS ]
ME9565000 | [REACH Registrations]
Active | [HS Code ]
29341000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 | [Hazardous Substances Data]
210880-92-5(Hazardous Substances Data) | [Toxicity]
LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rats (mg/l): >6.1 inhalation; LC50 in bobwhite quail, mallard duck (ppm): >5200, >5200 (dietary); LC50 (96 hr) in rainbow trout, bluegill (mg/l): >100, >120 (Ohkawara) |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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