| Identification | More | [Name]
Ginsenoside Rg1 | [CAS]
22427-39-0 | [Synonyms]
(3b,6a,12b)-3,12-dihydroxydammar-24-ene-6,20-diylbis(beta-d-glucopyranoside)
GINSENOSIDE RG1
GINSENOSIDE RGL
PANAXOSIDE A
SANCHINOSIDE C1
SANCHINOSIDE C1,PANAXOSIDE A
(6)-beta-d-glucopyranosyl-(20)-beta-d-glucopyranosyl-20s-protopanaxatriol
ginsenosidea2
ginsenosideg1
panaxosiderg1
(3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diylbis[beta-D-glucopyranoside]
Ginsenoside Rg1 std.
Ginsenoside Rg1 (CAS# 22427-39-0)
Gensenoside Rg1
GINSENOSIDE RG1 WITH HPLC
GINSENOSIDE-RG1 (GINSENOSIDE A2: GINSENOSIDE G1)
dihydroxydammar-24-ene-6,20-diylbis-
β-D-Glucopyranoside, (3β,6α,12β)-3,12-
(3β,6α,12β)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-β-D-glucopyranoside
[3β,12β-Dihydroxy-5α-dammar-24-ene-6α,20-diyl]bis(β-D-glucopyranoside) | [EINECS(EC#)]
244-989-9 | [Molecular Formula]
C42H72O14 | [MDL Number]
MFCD00210293 | [Molecular Weight]
801.01 | [MOL File]
22427-39-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
194～197℃ | [Boiling point ]
898.5±65.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) | [form ]
neat | [pka]
12.91±0.70(Predicted) | [color ]
White to Off-White | [Detection Methods]
NMR,HPLC | [Stability:]
Hygroscopic | [InChIKey]
YURJSTAIMNSZAE-OLCOBRLXNA-N | [LogP]
1.670 (est) | [CAS DataBase Reference]
22427-39-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S2:Keep out of the reach of children .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
3 | [RTECS ]
LY9537200 | [HS Code ]
29389090 |
| Hazard Information | Back Directory | [Description]
Ginsenoside RG1(Rg1) is a natural product found in Panax notoginseng, Panax ginseng, and Panax vietnamensis. It is one of the primary bioactive ingredients in Panax notoginseng saponins. Numerous studies have indicated that Rg1 plays significant roles in health benefits such as anticancer, neuroprotective, anti-senescence, anti-inflammation, and antioxidative effects. Also, extensive research has demonstrated that Rg1 is associated with various diseases, including cardiovascular disease, Alzheimer’s disease, spinal cord injury, and liver injury. Xue et al. and Yu et al. demonstrated that Rg1 ameliorated streptozotocin-induced oxidative stress and myocardial apoptosis and suppressed HG-induced mesenchymal activation and fibrosis[1].
| [Chemical Properties]
White solid | [Uses]
Ginsenoside Rg1 protects against arthitis through osteoclast differentiation inhibition. Anti-tumor agent, inhibits the NF-kB-dependant MMP-expression in PMA (phorbol myristate acetate)-induced tumor cell invasion. | [Definition]
ChEBI: A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 <ital pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 posit on. | [References]
[1] Hui Liu. “Ginsenoside Rg1 attenuates the inflammation and oxidative stress induced by diabetic nephropathy through regulating the PI3K/AKT/FOXO3 pathway.” Annals of translational medicine 9 24 (2021): 1789. |
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