| Identification | Back Directory | [Name]
FLUACRYPYRIM | [CAS]
229977-93-9 | [Synonyms]
na-83
Titaron
FLUACRYPYRIM
Fluacyrpyrim
Fluacrypyrim solution
fluacrypyrim (bsi, pa iso)
Fluacrypyrim Solution,100ppm
Fluacrypyrim@100 μg/mL in Methanol
Fluacrypyrim@1000 μg/mL in Acetonitrile
Methyl(E)-2-{α-[2-isopropoxy-6-(trifluoromethyl)pyrimidin-4-yloxy]-o-tolyl}-3-methoxyacrylate
Methyl (E)-2-[2-[[(2-isopropoxy-6-trifluoromethylpyrimidin-4-yl)oxy]methyl]phenyl]-3-methoxy-2-propenoate
methyl (E)-3-methoxy-2-[2-[[2-propan-2-yloxy-6-(trifluoromethyl)pyrimidin-4-yl]oxymethyl]phenyl]prop-2-enoate
(αE)-α-(Methoxymethylene-2-[[[2-(1-methylethoxy)-6-(trifluoromethyl)-4-pyrimidinyl]oxy]methyl]-benzeneacetic acid methyl ester
Benzeneacetic acid, α-(methoxymethylene)-2-[[[2-(1-methylethoxy)-6-(trifluoromethyl)-4-pyrimidinyl]oxy]methyl]-, methyl ester, (αE)- | [Molecular Formula]
C20H21F3N2O5 | [MDL Number]
MFCD06656582 | [MOL File]
229977-93-9.mol | [Molecular Weight]
426.39 |
| Chemical Properties | Back Directory | [Boiling point ]
529.9±60.0 °C(Predicted) | [density ]
1.258 | [storage temp. ]
0-6°C | [pka]
-2.07±0.32(Predicted) | [Henry's Law Constant]
3.0×102 mol/(m3Pa) at 25℃, MacBean (2012) |
| Hazard Information | Back Directory | [Description]
Fluacrypyrim is an acaricide. It has a low water solubility and is volatile. Little is known about its persistence in soil but it can be persistent in aquatic systems. It has a low level of toxicity to mammals. It shows a moderate to high level of toxicity to most aquatic species, earthworms and birds. It is not particularly toxic to honeybees. | [Uses]
Fluacrypyrim is used as a pesticide. A novel uterine relaxant with antinociceptive and anti-inflammatory properties. | [Definition]
ChEBI: Fluacrypyrim is a member of pyrimidines, an organofluorine acaricide, a methyl ester, an enoate ester and an enol ether. It has a role as a mitochondrial cytochrome-bc1 complex inhibitor. | [Production Methods]
The production of fluacrypyrim involves a multi-step organic synthesis built around constructing its pyrimidine-based acaricidal structure. The process begins with the preparation of (E)-2-(2'-chloromethyl)phenyl-3-methoxymethyl acrylate, which serves as a key intermediate. This compound is then reacted with 2-isopropoxy-4-hydroxy-6-trifluoromethylpyrimidine in the presence of potassium carbonate as a base and dimethylformamide as the solvent. The reaction mixture is heated to facilitate nucleophilic substitution, forming the desired fluacrypyrim molecule. | [Mechanism of action]
Mitochondrial complex III electron transport inhibitor - at Qo site. | [Pesticide Type]
Acaricide; Miticide; Insecticide |
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