| Identification | More | [Name]
Methyl 2-bromo-2-methylpropionate | [CAS]
23426-63-3 | [Synonyms]
2-BROMO-2-METHYLPROPIONIC ACID METHYL ESTER
2-BROMOISOBUTYRIC ACID METHYL ESTER
alpha-Bromoisobutyric acid methyl ester
METHYL 2-BROMO-2-METHYLPROPIONATE
METHYL 2-BROMOISOBUTYRATE
METHYL-2-BROMO-ISOBUTYRIC ACID
methyl a-bromobutyrate
METHYL A-BROMOISOBUTYRATE
METHYL ALPHA-BROMOISOBUTYRATE
Methyl Alpha-Bromobutyrate
2-Bromo-2-methylpropanoic acid methyl ester
2-Methyl-2-bromopropionic acid methyl ester
α-Bromoisobutyric acid methyl ester | [EINECS(EC#)]
245-657-6 | [Molecular Formula]
C5H9BrO2 | [MDL Number]
MFCD00017854 | [Molecular Weight]
181.03 | [MOL File]
23426-63-3.mol |
| Questions And Answer | Back Directory | [Synthesis]
Bromoisobutyric acid (4.17 g, 25 mmol) was dissolved in a solution of concentrated sulfuric acid (0.75 mL) and methanol (50 mL) and stirred under reflux for 2 h. The solution was then cooled to room temperature and concentrated under vacuum. The residue was dissolved in diethyl ether and washed with 10% aqueous sodium bicarbonate, washed with brine, dried under magnesium sulfate, and concentrated again under vacuum. A colorless oil was obtained (4.2 g, 23 mmol, 93% yield) 1H NMR (300 MHz, CDCl3) δ(ppm): 3.78 (s, 3H), 1.93 (s, 6H)
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| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 2929 6.1/PG 2
| [WGK Germany ]
3
| [F ]
19 | [HS Code ]
29159000 |
| Hazard Information | Back Directory | [Uses]
Atom Transfer Radical Polymerization (ATRP) initiator that will generate a polymer with a methyl end group | [Application]
Methyl 2-bromo-2-methylpropionate can be used as a free radical initiator to participate in polymerization reactions. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 43, p. 3684, 1978 DOI: 10.1021/jo00413a009 |
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