| Identification | More | [Name]
Methyl bromoacetate | [CAS]
96-32-2 | [Synonyms]
2-BROMOACETIC ACID METHYL ESTER
2-BROMOMETHYL ACETATE
BAM
BROMOACETIC ACID METHYL ESTER
BROMO METHYLACETATE
METHYL 2-BROMOACETATE
METHYL ALPHA-BROMOACETATE
METHYL BROMOACETATE
Aceticacid,bromo-,methylester
bromo-aceticacimethylester
Methyl bomoacetate
Methyl monobromoacetate
Methylester kyseliny bromoctove
methylesterkyselinybromoctove
methylmonobromoacetate
Methyl bromoacetate, 97+%
Methyl bromoacetate, 98+%
Methyl bromoacetate solution
Bromoacetic acid methyl | [EINECS(EC#)]
202-499-2 | [Molecular Formula]
C3H5BrO2 | [MDL Number]
MFCD00000189 | [Molecular Weight]
152.97 | [MOL File]
96-32-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless liquid | [Melting point ]
-50°C | [Boiling point ]
51-52 °C/15 mmHg (lit.) | [density ]
1.616 g/mL at 25 °C(lit.)
| [vapor pressure ]
18 hPa (50 °C) | [refractive index ]
n20/D 1.458(lit.)
| [Fp ]
145 °F
| [storage temp. ]
Store at R.T. | [form ]
Liquid | [color ]
Clear colorless to slightly yellow | [Specific Gravity]
1.416 | [Water Solubility ]
Miscible with methanol, ether and acetone. Slightly miscible with water | [FreezingPoint ]
<-50℃ | [Detection Methods]
GC,NMR | [BRN ]
506256 | [CAS DataBase Reference]
96-32-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetic acid, bromo-, methyl ester(96-32-2) | [EPA Substance Registry System]
96-32-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi,F | [Risk Statements ]
R25:Toxic if swallowed.
R34:Causes burns.
R37:Irritating to the respiratory system.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 2643 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
AF6300000
| [F ]
19 | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29159080 | [Safety Profile]
Poison by intravenous
route. When heated to decomposition it
emits toxic fumes of Br-. See also ESTERS. | [Hazardous Substances Data]
96-32-2(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
A colorless to straw-colored liquid with a sharp penetrating odor. Denser than water and soluble in water. Severly irritates skin and eyes. Toxic by ingestion and inhalation. Used to make vitamins and pharmaceuticals. | [Reactivity Profile]
METHYL BROMOACETATE(96-32-2) is a halogenated ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. | [Air & Water Reactions]
Highly flammable. Soluble in water. | [Hazard]
Vapor is strong irritant to eyes. | [Health Hazard]
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. | [Fire Hazard]
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. | [Chemical Properties]
Colorless liquid | [Uses]
Methyl bromoacetate was used in the synthesis of novel coumarins. It was also employed in the synthesis of cis-cyclopropanes | [Application]
Methyl Bromoacetate is an organic building block that has been used as a reactant in the preparation of isoquinolinone indole acetic acid derivatives as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseases. |
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