| Identification | Back Directory | [Name]
Alisol C monoacetate | [CAS]
26575-93-9 | [Synonyms]
23-Acetyl alisol C
Alisol C-monoacetat
Alisol C 23-acetate
23-O-Acetylalisol C
Alisol C monoacetate
Alisol C 23-monoacetate
Alisol C (23-acetate) (23-O-Acetylalisol C
(8α,9β,14β,23S,24R)-23-Acetoxy-11β-hydroxy-24,25-epoxydammar-13(17)-ene-3,16-dione
(8α,9β,14β,23S,24R)-23-Acetoxy-24,25-epoxy-11β-hydroxydammar-13(17)-ene-3,16-dione
(8α,9β,14β,23S,24R)-11β-Hydroxy-23-acetoxy-24,25-epoxy-5α-dammar-13(17)-ene-3,16-dione
Dammar-13(17)-ene-3,16-dione, 23-(acetyloxy)-24,25-epoxy-11-hydroxy-, (8α,9β,11β,14β,23S,24R)-
(1S,3R)-1-((R)-3,3-dimethyloxiran-2-yl)-3-((5R,8S,9S,10S,11S,14R)-11-hydroxy-4,4,8,10,14-pentamethyl-3,16-dioxo-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)butyl acetate | [Molecular Formula]
C32H48O6 | [MDL Number]
MFCD23379923 | [MOL File]
26575-93-9.mol | [Molecular Weight]
528.72 |
| Chemical Properties | Back Directory | [Boiling point ]
624.9±55.0 °C(Predicted) | [density ]
1.15 | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
14.36±0.70(Predicted) | [color ]
White | [InChIKey]
KOOCQNIPRJEMDH-QSKXMHMESA-N |
| Hazard Information | Back Directory | [Description]
Alisol C 23-acetate, a natural product extracted from Alisma orientale, can significantly and strongly inhibit DTH response after oral administration. | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Alisma orientalis. | [Uses]
Alisol C 23-acetate, a natural product extracted from Alisma orinentale, can significantly and strongly inhibit DTH response after oral administration. | [Biological Activity]
Alisol B 23-acetate produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. | [Synthesis]
100kg of raw materials crushed to 40 mesh, with 200kg concentration of 0.1% potassium hydroxide solution wetting for 4h, using a concentration of 80% ethanol extraction 3 times, each time the extraction of 2h, the extract is concentrated and ready for | [References]
[1] Lee JH, et al. The rhizomes of Alisma orientale and alisol derivatives inhibit allergic response and experimental atopic dermatitis. Biol Pharm Bull. 2012;35(9):1581-7. DOI:10.1248/bpb.b110689 |
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