ChemicalBook--->CAS DataBase List--->443683-76-9

443683-76-9

443683-76-9 Structure

443683-76-9 Structure
IdentificationBack Directory
[Name]

Alisol F 24-acetate
[CAS]

443683-76-9
[Synonyms]

Alisol F 24-acetate
Dammar-13(17)-en-3-one, 24-(acetyloxy)-16,23-epoxy-11,25-dihydroxy-, (8α,9β,11β,14β,23S,24R)-
(8alpha,9beta,11beta,14beta,23S,24R)-24-(Acetyloxy)-16,23-epoxy-11,25-dihydroxy-dammar-13(17)-en-3-one
[Molecular Formula]

C32H50O6
[MDL Number]

MFCD29917912
[MOL File]

443683-76-9.mol
[Molecular Weight]

530.75
Chemical PropertiesBack Directory
[Boiling point ]

634.3±55.0 °C(Predicted)
[density ]

1.16±0.1 g/cm3(Predicted)
[pka]

14.17±0.29(Predicted)
Hazard InformationBack Directory
[Uses]

Alisol F 24-acetate is a triterpene compound that can be isolated from the rhizomes of Alisma orientalis. Alisol F 24-acetate inhibits the secretion of HBV surface antigen HBsAg and HBeAg with IC50 values of 7.7 μM and 5.1 μM. Alisol F 24-acetate has proapoptotic activity and can be used for cancer research[1][2].
[References]

[1] Jiang ZY, et al. A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis. Planta Med. 2006 Aug;72(10):951-4. DOI:10.1055/s-2006-947178
[2] Pan G, et al. Alisol F 24 Acetate Enhances Chemosensitivity and Apoptosis of MCF-7/DOX Cells by Inhibiting P-Glycoprotein-Mediated Drug Efflux. Molecules. 2016 Feb 4;21(2):183. DOI:10.3390/molecules21020183
Spectrum DetailBack Directory
[Spectrum Detail]

Alisol F 24-acetate(443683-76-9)1HNMR
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