| Identification | Back Directory | [Name]
Alisol F 24-acetate | [CAS]
443683-76-9 | [Synonyms]
Alisol F 24-acetate
Dammar-13(17)-en-3-one, 24-(acetyloxy)-16,23-epoxy-11,25-dihydroxy-, (8α,9β,11β,14β,23S,24R)-
(8alpha,9beta,11beta,14beta,23S,24R)-24-(Acetyloxy)-16,23-epoxy-11,25-dihydroxy-dammar-13(17)-en-3-one | [Molecular Formula]
C32H50O6 | [MDL Number]
MFCD29917912 | [MOL File]
443683-76-9.mol | [Molecular Weight]
530.75 |
| Hazard Information | Back Directory | [Uses]
Alisol F 24-acetate is a triterpene compound that can be isolated from the rhizomes of Alisma orientalis. Alisol F 24-acetate inhibits the secretion of HBV surface antigen HBsAg and HBeAg with IC50 values of 7.7 μM and 5.1 μM. Alisol F 24-acetate has proapoptotic activity and can be used for cancer research[1][2]. | [References]
[1] Jiang ZY, et al. A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis. Planta Med. 2006 Aug;72(10):951-4. DOI:10.1055/s-2006-947178
[2] Pan G, et al. Alisol F 24 Acetate Enhances Chemosensitivity and Apoptosis of MCF-7/DOX Cells by Inhibiting P-Glycoprotein-Mediated Drug Efflux. Molecules. 2016 Feb 4;21(2):183. DOI:10.3390/molecules21020183 |
|
|