| Identification | More | [Name]
3-Bromobenzenesulfonyl chloride | [CAS]
2905-24-0 | [Synonyms]
3-BROMOBENZENE-1-SULFONYL CHLORIDE
3-BROMOBENZENESULFONYL CHLORIDE
3-BROMOBENZENESULPHONYL CHLORIDE
BUTTPARK 94\57-33
m-bromobenzenesulfonyl chloride
m-Bromobenzenesulfonyl | [EINECS(EC#)]
628-300-2 | [Molecular Formula]
C6H4BrClO2S | [MDL Number]
MFCD00052313 | [Molecular Weight]
255.52 | [MOL File]
2905-24-0.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to yellow liquid | [Melting point ]
30-33 °C | [Boiling point ]
90-91 °C/0.5 mmHg (lit.) | [density ]
1.773 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.593(lit.)
| [Fp ]
>110 °C
| [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Liquid | [color ]
Clear colorless to yellow | [Sensitive ]
Moisture Sensitive | [BRN ]
2691656 | [Stability:]
Moisture Sensitive | [InChI]
InChI=1S/C6H4BrClO2S/c7-5-2-1-3-6(4-5)11(8,9)10/h1-4H | [InChIKey]
PJGOLCXVWIYXRQ-UHFFFAOYSA-N | [SMILES]
C1(S(Cl)(=O)=O)=CC=CC(Br)=C1 | [CAS DataBase Reference]
2905-24-0(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Synthesis]
N-Chlorosilicate (0.6 mmol, 2.0 equivalent) was added in a single step to a solution of sulfonyl hydrazine (0.3 mmol) in acetonitrile (2 mL). The mixture was stirred at room temperature for 2 hours. The solvent was removed by vacuum evaporation, and the residue was purified by column chromatography (petroleum ether/ethyl acetate) to obtain the target product. 
Figure 3: Synthetic route of 3-Bromobenzenesulfonyl chloride |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xn | [Risk Statements ]
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Corrosive/Moisture Sensitive | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29049090 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to yellow liquid | [Uses]
3-Bromobenzenesulfonyl chloride may be used in the preparation of:
- 2-(3-bromophenyl)-5-n-butylfuran
- 2-(3-bromophenyl)-3,6-dimethyl-4,5,6,7-tetrahydrobenzofuran
- 3-bromo-4-(3-bromophenyl)thiophene
- 2,5-bis(3-bromophenyl)-1-methylpyrrole
| [General Description]
3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|