| Identification | More | [Name]
Melengestrol acetate | [CAS]
2919-66-6 | [Synonyms]
17ALPHA-ACETOXY-6-METHYL-16-METHYLENE-4,6-PREGNADIENE-3,20-DIONE
4,6-PREGNADIEN-6-METHYL-16-METHYLENE-17-OL-3,20-DIONE ACETATE
MELENGESTROL ACETATE
U-21240
20-dione,17-(acetyloxy)-6-methyl-16-methylene-pregna-6-diene-3
6-dehydro-16-methylene-6-methyl-17-acetoxyprogesterone
6-diene-3,20-dione,17-hydroxy-6-methyl-16-methylene-pregna-acetate
bdh1921
mga100
mga100(steroid)
Melengestrol Acerate
Melengesterol acetate
Melengestrol-acetate, Vetranal
MELENGESTROL ACETATE 99%
17α-acetoxy-6-methyl-16-methylene-4,6-pregnadiene-3,20-dione
17-(acetyloxy)-6-methyl-16-methylenepregna-4,6-diene-3,20-dione(9CI)
MELENGOESTROLACETATE
17a-Acetoxy-6-methyl-16-methylene-4,6-pregnadiene-3,20-dione
5373
NSC-70968 | [EINECS(EC#)]
220-859-7 | [Molecular Formula]
C25H32O4 | [MDL Number]
MFCD00072142 | [Molecular Weight]
396.52 | [MOL File]
2919-66-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
202-204 °C(lit.)
| [alpha ]
D23 -127° (c = 0.31 in chloroform) | [Boiling point ]
440.2°C (rough estimate) | [density ]
1.0911 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
Off-White to Beige | [BRN ]
2066919 | [Major Application]
clinical testing | [InChIKey]
UDKABVSQKJNZBH-DWNQPYOZSA-N | [SMILES]
C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(C)=O)(C(=O)C)C(=C)C3)C=C2C | [CAS DataBase Reference]
2919-66-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS08 | [Signal word ]
Warning | [Hazard statements ]
H361fd | [Precautionary statements ]
P201-P202-P280-P308+P313-P405-P501 | [Hazard Codes ]
Xn | [Risk Statements ]
R62:Possible risk of impaired fertility. | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
TU4141000
| [HS Code ]
29372390 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Repr. 2 | [Safety Profile]
An experimental
teratogen. Experimental reproductive
effects. When heated to decomposition it
yields acrid smoke and irritating fumes. | [Toxicity]
LD50 (mg/kg): >8000 orally in rats; >2500 i.p. in mice (Zimbelman) |
| Hazard Information | Back Directory | [Chemical Properties]
Light Tan Solid | [Uses]
antiarrhythmic, cardiotonic, hypertensive, Na/K ATPase inhibitor | [Uses]
Orally active progestational steroid. Progestogen; growth promotant. | [Definition]
ChEBI: Melengestrol acetate is a corticosteroid hormone. | [Synthesis]
U.S. Patent 3,359,287 discusses the preparation of melengestrol acetate by dehydrogenating 17α-hydroxy-6α-methyl-16-methylenepregn-4-en-3,20-dione-17-acetate with chloroquinone. U.S. Patent 4,154,748 discusses an interchangeable method in w | [Toxics Screening Level]
The initial threshold screening level (ITSL) for melengesterol acetate is 2 μg/m3 based on an annual averaging time. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Telephone: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
|