| Identification | More | [Name]
4-IMIDAZOLEACETIC ACID HYDROCHLORIDE | [CAS]
3251-69-2 | [Synonyms]
(1H-IMIDAZOL-4-YL)-ACETIC ACID HCL
2-(1H-IMIDAZOL-4-YL)ACETIC ACID HYDROCHLORIDE
4-CARBOXYMETHYLIMIDAZOLE HYDROCHLORIDE
4-IMIDAZOLEACETIC ACID HYDROCHLORIDE
I4AA HYDROCHLORIDE
IMIDAZOLE-4(5)-ACETIC ACID HYDROCHLORIDE
IMIDAZOLE-4-ACETIC ACID
IMIDAZOLE-4-ACETIC ACID HYDROCHLORIDE
IMIDAZOLE-4-ACETIC ACID MONOHYDROCHLORIDE
IMIDAZOLEACETIC ACID HCL
IMIDAZOLE-4-ACETIC ACID HCL
IMIDAZOLE-4-ACETIC ACID HYDROCHLORIDE (I 4AA) COMPETITIVE GA
4-IMIDAZOLEACETIC ACID HYDROCHLORIDE, 98 %
Imidazolyl-4-AceticAcidHcl
IMIDAZOLEACETIC ACID HYDROCHLORIDE
(4-imidazolyl)acetic acid hydrochloride
4-IMIDAZOLEACETICACIDHCL
(4-Imidazolyl)acetic acid hydrochloride, I4AA | [EINECS(EC#)]
221-840-6 | [Molecular Formula]
C5H7ClN2O2 | [MDL Number]
MFCD00012698 | [Molecular Weight]
162.57 | [MOL File]
3251-69-2.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER | [Melting point ]
218-222 °C(lit.)
| [storage temp. ]
2-8°C | [solubility ]
water: soluble100mg/mL, clear, faintly yellow | [form ]
Crystalline Powder | [color ]
White to light yellow | [Water Solubility ]
Soluble in water. | [Sensitive ]
Hygroscopic | [BRN ]
3701591 | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C5H6N2O2.ClH/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);1H | [InChIKey]
MWHLCFYPFGFBQO-UHFFFAOYSA-N | [SMILES]
C1(CC(=O)O)N=CNC=1.Cl | [CAS DataBase Reference]
3251-69-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H335-H315-H319 | [Precautionary statements ]
P271-P261-P280 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [HazardClass ]
IRRITANT | [HS Code ]
29332900 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER | [Uses]
A GABAc antagonistImidazole-4-acetic acid monohydrochloride is used in the preparation of imidazolyl-polyethylenimine modified nanoparticles. It is also used to prepare pyridyl and imidazoyl functionalized carboproteins and potential metal ion chelators. Further, it acts as an imidazole derivative with potential antituberculousis properties. In addition to this, it is used in the generation of acyl guanidine inhibitors of beta-secretas. | [Biological Activity]
Competitive antagonist at GABAC receptors. | [Synthesis]
4-Imidazoleacetic acid hydrochloride is synthesized by reaction of imidazole-4(5)-acetic acid,amidine and dilute hydrochloric acid.
| [in vivo]
Imidazoleacetic acid (400 mg/kg; i.p.; single dose) hydrochloride increases the total free GABA pool size in mouse brain without a concomitant increase in the biosynthesis of GABA from glutamate[2].
| [IC 50]
Microbial Metabolite; Human Endogenous Metabolite |
|
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Unibest Pharmaceutical Technology Co., Ltd. Gold
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