ChemicalBook--->CAS DataBase List--->36167-63-2

36167-63-2

36167-63-2 Structure

36167-63-2 Structure
IdentificationMore
[Name]

Halofantrine hydrochloride
[CAS]

36167-63-2
[Synonyms]

1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenathrenemethanol hydrochloride
halofantrine hydrochloride
1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)phenanthren-1-methanol hydrochloride
Halofantarine HCL
Halfan, 1,3-Dichloro-a-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenanthrenemethanol hydrochloride
Halfan
[EINECS(EC#)]

252-895-4
[Molecular Formula]

C26H30Cl2F3NO.HCl;C26H31Cl3F3NO
[MDL Number]

MFCD00879136
[MOL File]

36167-63-2.mol
[Molecular Weight]

536.88
Chemical PropertiesBack Directory
[Melting point ]

93-96°; mp 203-204°
[storage temp. ]

2-8°C
[solubility ]

DMSO: >10mg/mL
[form ]

solid
[color ]

white to off-white
[Major Application]

pharmaceutical (small molecule)
[InChI]

1S/C26H30Cl2F3NO.ClH/c1-3-5-10-32(11-6-4-2)12-9-25(33)23-16-22-21(14-18(27)15-24(22)28)20-13-17(26(29,30)31)7-8-19(20)23;/h7-8,13-16,25,33H,3-6,9-12H2,1-2H3;1H
[InChIKey]

WANGFTDWOFGECH-UHFFFAOYSA-N
[SMILES]

Cl.CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c3cc(ccc13)C(F)(F)F
[CAS DataBase Reference]

36167-63-2(CAS DataBase Reference)
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Antimalarial.
[Brand name]

Halfan (GlaxoSmithKline).
[Biological Activity]

Halofantrine is a blocker of delayed rectifier potassium current via the inhibition of hERG channel.
[IC 50]

Plasmodium
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

SF7790000
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Aquatic Chronic 4
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