ChemicalBook--->CAS DataBase List--->372-47-4

372-47-4

372-47-4 Structure

372-47-4 Structure
IdentificationMore
[Name]

3-Fluoropyridine
[CAS]

372-47-4
[Synonyms]

3-FLUOROPYRIDINE
Pyridine, 3-fluoro-
3-Fluoroypyridine
3-FLUOROPYRIDINE 98% (GC)
3-Fluoropyridine,98%
3-Fluoropyridine 98%
[EINECS(EC#)]

206-755-4
[Molecular Formula]

C5H4FN
[MDL Number]

MFCD00006374
[Molecular Weight]

97.09
[MOL File]

372-47-4.mol
Chemical PropertiesBack Directory
[Appearance]

CLEAR YELLOW LIQUID
[Melting point ]

251-254°C (dec.)
[Boiling point ]

107-108 °C (lit.)
[density ]

1.13 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.472(lit.)
[Fp ]

56 °F
[storage temp. ]

Flammables area
[form ]

Liquid
[pka]

pK1:2.97(+1) (25°C)
[color ]

Clear yellow
[Specific Gravity]

1.130
[BRN ]

105702
[InChI]

InChI=1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H
[InChIKey]

CELKOWQJPVJKIL-UHFFFAOYSA-N
[SMILES]

C1=NC=CC=C1F
[CAS DataBase Reference]

372-47-4(CAS DataBase Reference)
[NIST Chemistry Reference]

3-F-pyridine(372-47-4)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H315-H319-H335
[Precautionary statements ]

P210-P302+P352-P305+P351+P338
[Hazard Codes ]

F,Xi,Xn
[Risk Statements ]

R11:Highly Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S33:Take precautionary measures against static discharges .
S7/9:Keep container tightly closed and in a well-ventilated place .
[RIDADR ]

UN 1993 3/PG 2
[WGK Germany ]

3
[Hazard Note ]

Flammable/Irritant
[HazardClass ]

3
[PackingGroup ]

II
[HS Code ]

29333990
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Eye Irrit. 2
Flam. Liq. 2
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

3-Bromo-5-fluoropyridine-->3-Fluoro-4-bromopyridine
[Preparation Products]

5-Fluoro-2-picolinic acid-->4-CHLORO-3-FLUOROPYRIDINE HCL-->2-Chloro-3-fluoropyridine-4-carboxylic acid-->4-Amino-3-fluoropyridine-->3-Fluoropyridine-2-carboxylic acid-->3-FLUOROPYRIDINE-4-BORONIC ACID-->3-FLUORO-2-IODOPYRIDINE-4-CARBOXYLIC ACID-->3-Fluoropyridine-4-carboxylic acid-->3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-->AMG 925-->1-(3-Pyridinyl)piperazine-->3-FLUORO-4-IODOPYRIDINE
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

3-Fluoropyridine(372-47-4).msds
Hazard InformationBack Directory
[Chemical Properties]

CLEAR YELLOW LIQUID
[Uses]

3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters.
[Preparation]

A combination of CsF and HF provides a very reactive fluoride source and has shown faint promise with 3-chloropyridine giving 3-fluoropyridine in a very low yield.
synthesis of 3-Fluoropyridine
[General Description]

3-Fluoropyridine is oxidized to corresponding N-oxides, which on treatment with hot acetic anhydride and hydrolysis yields 3-halo-2-pyridones. Microwave spectrum of 3-fluoropyridine has been investigated in the frequency range of 8-18GHz at dry ice temperature. Deprotonation of 3-fluoropyridine with Bu3MgLi in THF at -10°C has been studied.
Spectrum DetailBack Directory
[Spectrum Detail]

3-Fluoropyridine(372-47-4)MS
3-Fluoropyridine(372-47-4)1HNMR
3-Fluoropyridine(372-47-4)IR1
3-Fluoropyridine(372-47-4)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

3-Fluoropyridine, 99%(372-47-4)
[Alfa Aesar]

3-Fluoropyridine, 98%(372-47-4)
[Sigma Aldrich]

372-47-4(sigmaaldrich)
[TCI AMERICA]

3-Fluoropyridine,>98.0%(GC)(372-47-4)
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