| Identification | More | [Name]
6-Fluoronicotinic acid | [CAS]
403-45-2 | [Synonyms]
2-FLUORO-5-PYRIDINE CARBOXYLIC ACID
2-Fluoro-5-pyridine carboxylic acid(6-Fluoronicotinic acid)
2-FLUOROPYRIDINE-5-CARBOXYLIC ACID
6-FLUORO-3-PYRIDINECARBOXYLIC ACID
6-FLUORONICOTINIC ACID
6-FLUOROPYRIDINE-3-CARBOXYLIC ACID
6-FLUOROPYRIDINE-3-FORMIC ACID
6-Fluoronicotinic acid 98%
6-Fluoronicotinicacid98%
3-Pyridinecarboxylic acid,6-fluoro- | [EINECS(EC#)]
251-228-4 | [Molecular Formula]
C6H4FNO2 | [MDL Number]
MFCD01859863 | [Molecular Weight]
141.1 | [MOL File]
403-45-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
144-148 °C(lit.) | [Boiling point ]
309.4±22.0 °C(Predicted) | [density ]
1.419±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
3.41±0.10(Predicted) | [color ]
White to Orange to Green | [Detection Methods]
HPLC | [InChI]
InChI=1S/C6H4FNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10) | [InChIKey]
UJDLCTNVHJEBDG-UHFFFAOYSA-N | [SMILES]
C1=NC(F)=CC=C1C(O)=O | [CAS DataBase Reference]
403-45-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
White solid | [Uses]
It is used as a pharmaceutical intermediate. | [References]
[1] LATIFA RBAH-VIDAL. Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [¹⁰F]ICF01006, a highly promising melanoma PET tracer.[J]. European Journal of Nuclear Medicine and Molecular Imaging, 2012, 39 9: 1449-1461. DOI:10.1007/s00259-012-2168-y.
[2] FALGUNI BASULI. Fast indirect fluorine-18 labeling of protein/peptide using the useful 6-fluoronicotinic acid-2,3,5,6-tetrafluorophenyl prosthetic group: A method comparable to direct fluorination.[J]. Journal of labelled compounds & radiopharmaceuticals, 2017, 60 3 1: 168-175. DOI:10.1002/jlcr.3487.
[3] G. F. HAWKINS ARTHUR R. THE PREPARATION OF 5-FLUORONICOTINIC ACID AND 5-FLUORONICOTINAMIDE1[J]. The Journal of Organic Chemistry, 1949, 14 2: 328-332. DOI:10.1021/jo01154a021.
[4] Lal, Achchhe, and Devendra Kumar Singh. "Theoretical and Experimental Studies of Vibrational Spectra of 6-fluoronicotinc Acid." |
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