ChemicalBook--->CAS DataBase List--->400775-35-1

400775-35-1

400775-35-1 Structure

400775-35-1 Structure
IdentificationBack Directory
[Name]

Bis-Propargyl-PEG7
[CAS]

400775-35-1
[Synonyms]

CAS_400775-35-1
Bis-Propargyl-PEG7
4,7,10,13,16,19,22-Heptaoxapentacosa-1,24-diyne
[Molecular Formula]

C18H30O7
[MDL Number]

MFCD10699797
[MOL File]

400775-35-1.mol
[Molecular Weight]

358.43
Chemical PropertiesBack Directory
[Boiling point ]

421.9±40.0 °C(Predicted)
[density ]

1.061±0.06 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
[form ]

Solid-Liquid Mixture
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Bis-propargyl-PEG7 is a homobifunctional reagent with two propargyl groups that can be used to form triazole linkages with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The hydrophilic PEG units help improve the solubility of the molecule in aqueous environment.
[Uses]

Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates[1]. Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[IC 50]

PEGs
[References]

[1] Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates. WO2018041942A1.
Spectrum DetailBack Directory
[Spectrum Detail]

Bis-Propargyl-PEG7(400775-35-1)1HNMR
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