ChemicalBook--->CAS DataBase List--->1351373-46-0

1351373-46-0

1351373-46-0 Structure

1351373-46-0 Structure
IdentificationBack Directory
[Name]

Bis-propargyl-PEG8
[CAS]

1351373-46-0
[Synonyms]

[Molecular Formula]

C20H34O8
[MDL Number]

MFCD31580135
[MOL File]

1351373-46-0.mol
[Molecular Weight]

402.48
Chemical PropertiesBack Directory
[Boiling point ]

459.7±40.0 °C(Predicted)
[density ]

1.067±0.06 g/cm3(Predicted)
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Bis-propargyl-PEG8 consists of two propargyl groups which can react with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry to form stable triazole linkage.
[Uses]

Bis-propargyl-PEG7 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG7 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates[1]. Bis-propargyl-PEG7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[IC 50]

PEGs
[References]

[1] Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates. WO2018041942A1.
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