| Identification | Back Directory | [Name]
Bis-propargyl-PEG6 | [CAS]
185378-83-0 | [Synonyms]
Bis-propargyl-PEG6
Alkyne-PEG6-Alkyne
PROPARGYL-PEG6-PROPARGYL
4,7,10,13,16,19-Hexaoxadocosa-1,21-diyne | [Molecular Formula]
C16H26O6 | [MDL Number]
MFCD26793755 | [MOL File]
185378-83-0.mol | [Molecular Weight]
314.37 |
| Chemical Properties | Back Directory | [Boiling point ]
381.7±37.0 °C(Predicted) | [density ]
1.053±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Oil | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Bis-propargyl-PEG6 has two propargyl groups which can participate in Click Chemistry reactions to yield a stable triazole linkage with azide compounds; copper is needed as a catalyst. The 6 units of PEG increase the hydrophilicity of the compound. | [Uses]
Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity[1]. Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Anti-Zika Activity of a Library of Synthetic Carbohydrate Receptors. DOI: 10.1021/acs.jmedchem.9b00142. DOI:10.1021/acs.jmedchem.9b00142 |
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Henan Alfachem Co.,Ltd.
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0371-0371-0371-55051623 18137891487 |
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www.chemicalbook.com/supplier/14555231/ |
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