| Identification | More | [Name]
5-Bromopyrimidine | [CAS]
4595-59-9 | [Synonyms]
2-BROMOPYRIMIDINE
5-BROMOPYRIMIDINE
PYRIMIDINE, 2-BROMO-
PYRIMIDINE, 5-BROMO-
5-bromo-pyrimidin
5-Bromopyrimidine,98%
Pyrimidine,5-bromo-(6CI,7CI,8CI,9CI)
5-BROMOPYRIMIDINE, 99% MIN
5-BROMOPYRIMIDINE 0.98
5-BROMOISATINIC ANHYDRIDE | [EINECS(EC#)]
224-992-1 | [Molecular Formula]
C4H3BrN2 | [MDL Number]
MFCD00014601 | [Molecular Weight]
158.98 | [MOL File]
4595-59-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Yellow Solid | [Melting point ]
67-73 °C (lit.) | [Boiling point ]
168°C(lit.) | [density ]
1.6448 (rough estimate) | [refractive index ]
1.5260 (estimate) | [storage temp. ]
Keep Cold | [solubility ]
Soluble in chloroform. | [form ]
Crystalline Powder or Chunks | [pka]
1.40±0.10(Predicted) | [color ]
Yellow to beige-brown | [Usage]
Intermediate fr life science products Attributes For further information please contact us Contact | [Detection Methods]
HPLC | [BRN ]
107326 | [InChI]
InChI=1S/C4H3BrN2/c5-4-1-6-3-7-2-4/h1-3H | [InChIKey]
GYCPLYCTMDTEPU-UHFFFAOYSA-N | [SMILES]
C1=NC=C(Br)C=N1 | [CAS DataBase Reference]
4595-59-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Pyrimidine, 5-bromo-(4595-59-9) | [EPA Substance Registry System]
4595-59-9(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R36/38:Irritating to eyes and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT, KEEP COLD | [HS Code ]
29335900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Description]
5-Bromopyrimidine is an important structural unit in organic compounds, featuring a bromine functional group on its pyrimidine ring which serves as the active moiety enabling participation in diverse chemical reactions. Through acid-catalysed electrophilic alkylation of aromatic compounds with 5-bromopyrimidine, followed by oxidative rearrangement to form the dihydropyrimidine ring. Subsequent Sonogashira cross-coupling enables the preparation of 4-aryl-5-pyrimidylacetylene derivatives, which possess medicinal value. | [Chemical Properties]
Yellow Solid | [Uses]
Intermediate fr life science products Attributes For further information please contact us Contact | [Application]
5-Bromopyrimidine is a compound useful in organic synthesis. | [Preparation]
5-Bromopyrimidine is prepared by reacting dibromodifuranone with formamide in the presence of B2O2 catalyst at 180-185°C to obtain the product. | [General Description]
Rapid nucleophilic displacement reactions of 5-bromopyrimidine with nucleophiles under microwave irradiation has been studied. 5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine. |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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