| Identification | Back Directory | [Name]
m-PEG7-Ms | [CAS]
477775-57-8 | [Synonyms]
m-PEG8-Ms
m-PEG7-Ms
20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane | [Molecular Formula]
C16H34O10S | [MDL Number]
MFCD29060063 | [MOL File]
477775-57-8.mol | [Molecular Weight]
418.5 |
| Hazard Information | Back Directory | [Description]
m-PEG8-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG7-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG7-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Cleavable Linker; PEGs | [References]
[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1. |
|
|