| Identification | More | [Name]
3-Hydroxypivalic acid | [CAS]
4835-90-9 | [Synonyms]
2,2-DIMETHYL-3-HYDROXYPROPIONIC ACID
2,2'-THIO-BIS[ETHANOL]
2,2'-THIODIETHANOL
2,2-THIODIETHANOL
2-HYDROXYETHYL SULFIDE
3-HYDROXY-2,2-DIMETHYLPROPANOIC ACID
3-Hydroxypivalic acid
BETA-THIODIGLYCOL
BIS(2-HYDROXYETHYL) SULFIDE
HYDROXYPIVALIC ACID
OMEGA,OMEGA'-DIHYDROXYETHYL SULFIDE
THIODIETHYLENE GLYCOL
THIODIGLYCOL
THYODIGLYCOL
3-hydroxy-2,2-dimethyl-propanoicaci
Propanoic acid, 3-hydroxy-2,2-dimethyl-
2,2-DIMETHYL-3-HYDROXYPROPANOIC ACID | [EINECS(EC#)]
203-874-3 | [Molecular Formula]
C5H10O3 | [MDL Number]
MFCD00002910 | [Molecular Weight]
118.13 | [MOL File]
4835-90-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
−16 °C(lit.)
| [Boiling point ]
164-166 °C20 mm Hg(lit.)
| [density ]
1.221 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.446Pa at 25℃ | [refractive index ]
n20/D 1.5215(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Sparingly, Heated), Methanol (Slightly) | [form ]
powder to crystal | [pka]
4.55±0.10(Predicted) | [color ]
White to Almost white | [Water Solubility ]
Soluble in water. | [BRN ]
1747025 | [LogP]
-0.02 | [CAS DataBase Reference]
4835-90-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Hydroxy pivalic acid(4835-90-9) | [EPA Substance Registry System]
4835-90-9(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H318 | [Precautionary statements ]
P280i-P305+P351+P338-P310a | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
1
| [RTECS ]
KM2975000
| [F ]
3-13-23 | [TSCA ]
Yes | [HS Code ]
2918.19.9000 | [REACH Registrations]
Active |
| Hazard Information | Back Directory | [Chemical Properties]
white crystal | [Uses]
3-Hydroxy-2,2-dimethylpropionic acid is used as pharmaceutical intermediate. | [Reactions]
When 3-Hydroxypivalic acid (1r)
was used under standard conditions, the free hydroxyl group was
well tolerated and after conjugated addition, the lactonization took
place smoothly to afford compound 3ra as a single
diastereoisomer (according to 1H- and 13C-NMR)[1].
Tandem decarboxylation-Giese reaction-lactonization
| [Flammability and Explosibility]
Notclassified | [References]
[1] NIEVES P. RAMIREZ; Jose C G G. Decarboxylative Giese-Type Reaction of Carboxylic Acids Promoted by Visible Light: A Sustainable and Photoredox-Neutral Protocol[J]. European Journal of Organic Chemistry, 2017. DOI:10.1002/ejoc.201601478. |
|
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Alfa Aesar
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Energy Chemical
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Maya High Purity Chemicals
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