ChemicalBook--->CAS DataBase List--->50629-82-8

50629-82-8

50629-82-8 Structure

50629-82-8 Structure
IdentificationMore
[Name]

Halometasone
[CAS]

50629-82-8
[Synonyms]

2-chlor-6a,9-difluor-11b,17,21-trihydroxy-16a-methyl-1,4-pregnadien-3,20-dion
2-chloroflumethasone
HALOMETASONE
HALOMETASONE HYDRATE
HALOMETASONE MONOHYDRATE
(6α,11β,16α)-2-Chloro-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Halomethasone
Sicorten
2-Chloro-6a,9-difluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione
2-Chloro-6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
[EINECS(EC#)]

256-664-9
[Molecular Formula]

C22H27ClF2O5
[MDL Number]

MFCD00866091
[Molecular Weight]

444.9
[MOL File]

50629-82-8.mol
Chemical PropertiesBack Directory
[Melting point ]

220-222° (dec)
[Boiling point ]

600.5±55.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

Acetone (Sparingly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

11.93±0.70(Predicted)
[color ]

White to Off-White
[InChIKey]

GGXMRPUKBWXVHE-KRIIOHHINA-N
[SMILES]

[C@@]12([H])C[C@@H](C3=CC(=O)C(Cl)=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@]1(C)[C@@]([C@H](C)C[C@@]21[H])(O)C(=O)CO)F |&1:0,3,11,13,15,18,20,21,24,r|
[CAS DataBase Reference]

50629-82-8(CAS DataBase Reference)
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Chloroflumethasone(50629-82-8).msds
Hazard InformationBack Directory
[Description]

Halometasone is a Dotent, topical steroid useful in a variety of acute and chronic eczematous dermaioses and psoriasis. It is reportedly devoid of skin toxicity and systemic effects.
[Chemical Properties]

Melting point 220~222℃ (decomposition).
[Originator]

Ciba-Geigy (Switzerland)
[Uses]

A corticosteroid used in the treatment of skin disorders such as chronic eczema.
[Definition]

ChEBI: Halometasone is a 21-hydroxy steroid.
[Brand name]

SICORTEN
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