| Identification | More | [Name]
[2R*(4R*,8R*)]-(+/-)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate | [CAS]
51898-34-1 | [Synonyms]
[2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)CHROMAN-6-YL] PYRIDINE-3-CARBOXYLATE
ALPHA-TOCOPHERYL NICOTINATE
VITAMIN E NICOTINATE
(+/-)-a-tocopherolnicotinate
3,4-dihydro-2,5,7,8-tetramehyl-2(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ylester,[2R(4R,8R)]3-Pyridnecarboxyicacid
vitaminenicotinate,tocopherylnicotinate
3,4-dihydro-2,5,7,8-tetramehyl-2(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R(4R,8R)]3-Pyridnecarboxyic acid
[2R*(4R*,8R*)]-(±)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate
VITAMIN E NICOTINATE(DL-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECY) CHROMANOL-6-NICOTINIC )
DL-α-Tocopherol nicotinate
3-Pyridinecarboxylic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel-(9CI)
3-Pyridinecarboxylic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-
3-Pyridinecarboxylic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+-)-
DL-a-Tocopheryl nicotinate
3,4-dihydro-2,5,7,8-tetramehyl-2(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R(4R,8R)]3-Pyridnecarboxyic acid
[2R*(4R*,8R*)]-(+/-)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate
Tocopherol nicotinate
Vitamin E nicotinate
Vitamin E Nicotinamite
Juvela nicotinate | [EINECS(EC#)]
257-501-4 | [Molecular Formula]
C35H53NO3 | [MDL Number]
MFCD00057302 | [Molecular Weight]
535.8 | [MOL File]
51898-34-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
approximate 38℃ | [alpha ]
[α]D20 0±0.5゜ (c=5, C2H5OH) | [Boiling point ]
649.0±55.0 °C(Predicted) | [density ]
0.9611 g/cm3 | [storage temp. ]
2-8°C
| [form ]
Solid | [pka]
3.03±0.10(Predicted) | [color ]
White to off-white | [Cosmetics Ingredients Functions]
SKIN CONDITIONING
SKIN PROTECTING
ANTIOXIDANT | [InChIKey]
MSCCTZZBYHQMQJ-AZAGJHQNSA-N | [SMILES]
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)c3cccnc3)c(C)c(C)c2O1 | [Uses]
tocopherol nicotinate is used as an anti-oxidant and a skin-conditioning agent. | [CAS DataBase Reference]
51898-34-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Definition]
ChEBI: Tocopheryl nicotinate is a tocol. | [Biological Activity]
α-Tocopherol is a radical-chain breaker owing to its anti-oxidant property.''Tocopherols (TCP) (vitamin E) are a series (αβγ and δ) of chiral organic molecules th at vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants th at protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol nicotinate is used along the α-Tocopherol acetateα-Tocopherol succinate and other esterified forms as a vitamin E supplement with similar but differential activities. | [in vivo]
(±)-α-Tocopherol nicotinate (Vitamin E) (in animal feedings, 50 mg/kg or 585 mg/kg, 7 weeks) significantly increases the proportion of CD4+CD8- T cells and the expression of ICAM-1 in thymic epithelial cells (TECs) isolated of male Fisher rats at high dose concentrations of 585 mg/kg compared to low dose treatment of 50 mg/kg[2].
| [storage]
Store at -20°C |
|
| Company Name: |
Spectrum Chemical Manufacturing Corp.
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| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
T&W GROUP
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| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
| Company Name: |
Puripharm Co., Ltd.
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| Telephone: |
0572-2745768-1 13167223168;13167223168 |
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http://www.puriactives.com/ |
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