| Identification | More | [Name]
4-Aminoindole | [CAS]
5192-23-4 | [Synonyms]
1H-INDOL-4-AMINE
1H-INDOL-4-YLAMINE
4-AMINO-1H-INDOLE
4-INDOLAMINE
INDOLE-4-AMINE
4-Aminoindole
4-Indolamine
5-methoxyl indole-carboxaldehyde
4-AMINOINDOLINE/4-INDOLAMINE
4-Aminoindole ,97% | [EINECS(EC#)]
621-202-0 | [Molecular Formula]
C8H8N2 | [MDL Number]
MFCD01076559 | [Molecular Weight]
132.16 | [MOL File]
5192-23-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Greenish-grey to tan powder | [Melting point ]
106-109 °C (lit.) | [Boiling point ]
354.0±15.0 °C(Predicted) | [density ]
1.268±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [form ]
powder to crystal | [pka]
18.23±0.30(Predicted) | [color ]
White to Gray to Brown | [Water Solubility ]
Insoluble | [Sensitive ]
Air Sensitive | [Detection Methods]
HPLC | [BRN ]
114919 | [CAS DataBase Reference]
5192-23-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
8-10-34 | [HazardClass ]
AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
Greenish-grey to tan powder | [Uses]
Reactant for preparation of:• ;Inhibitors of bacterial thymidylate synthase1• ;Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)2• ;Inhibitors of Gli1-mediated transcription in the Hedgehog pathway3• ;Protein kinase C θ (PKCθ) inhibitors4• ;Indolic non-peptidic HIV protease inhibitors5• ;Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists6• ;Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors7• ;11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibi | [Definition]
ChEBI: 4-Aminoindole is a member of indoles. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 48, p. 5130, 1983 DOI: 10.1021/jo00173a071 | [General Description]
4-Aminoindole is an indole derivative. Its cytokinin activity has been assessed by tobacco pith callus bioassay. 4-Aminoindole can be prepared by reacting 2,6-dinitrotoluene and N,N-dimethylformamide dimethylacetal in anhydrous DMF. |
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