| Identification | More | [Name]
4,4'-((2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1,1-dimethyl-piperazinium) dibromide | [CAS]
52212-02-9 | [Synonyms]
4,4'-((2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)androstane-2,16-diyl)bis(1,1-dimethyl-piperazinium) dibromide
pipecuronium bromide
4,4'-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetoxy)androstane-2,16-diyl]bis[1,1-dimethylpiperazinium] dibromide
PIPECURIUM BROMIDE
Pipecuronium
PIPECURINIUM BROMIDE
4,4'-((2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1,1-dimethyl-piperazinium) dibromide
4，4’-[(2β，3α，5α，16β，17β)-3，17-Bis(acetoxy)andrc~tane-2，16-diyl]bis(1，1-dimethylpiperazinium)dibromide
Ardtm
Pipecuriurn Brmnide
RGH-1106
[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-2,16-bis(4,4-dimethyl-2,3,5,6-tetrahydropyrazin-1-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate dibromide
Androstane, piperazinium deriv.
Arduan
Piperazinium, 4,4'-[(2b,3a,5a,16b,17b.)-3,17-bis(acetyloxy)androstane-2,16-diyl]bis[1,1-dimethyl-, bromide (1:2) | [EINECS(EC#)]
257-740-4 | [Molecular Formula]
C35H62Br2N4O4 | [MDL Number]
MFCD00867696 | [Molecular Weight]
762.699 | [MOL File]
52212-02-9.mol |
| Hazard Information | Back Directory | [Chemical Properties]
Crystallized from dichloromethane and acetone, melting point 262-264°C (decomposition). [α] D 23 + 8.1° (C = 1, water). Acute toxicity LD50 in mice and rats (mg/kg): 29.7, 172.6 by intravenous injection; 70.6, 449.6 by intraperitoneal injection. | [Uses]
Pipecuronium Bromide is a muscle relaxant and an anaesthesia used in patients undergoing coronary artery bypass graft surgery. | [Definition]
ChEBI: Pipecuronium bromide is a steroid ester. | [Brand name]
Arduan (Organon). | [General Description]
Pipecurium bromide, 4,4 -(3 ,17 -dihydroxy-5 -androstan-2 ,16 -ylene)bis(1,1-dimeth-ylpiperazinium)dibromide diacetate (Arduan), is anondepolarizing muscle relaxant similar, both chemicallyand clinically, to pancuronium bromide. It is a long-actingdrug indicated as an adjunct to anesthesia and in patients undergoingmechanical ventilation. | [Pharmacology]
Pipecuronium bromide, an analogue of pancuronium, was developed in
Hungary in 1980 and is marketed in Eastern Europe and the United S tates.
The intubating dose is 0.07 mg kg–1. The onset time and time to recovery from
block are similar to those of pancuronium, and excretion of
the drug through the kidneys is significant (66%). In contrast to
pancuronium, pipecuronium produces marked cardiovascular stability,
having no vagolytic or sympathomimetic effects. It may therefore be useful
during major surgery in patients with cardiac disease. | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Toxicity]
LD50 in mice, rats (mg/kg): 29.7, 172.6 i.v.; 70.6, 449.6 i.p.; 60.5, 455.8 s.c. (Kárpáti, Biro) |
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| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Finetech Industry Limited
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+86-27-8746-5837 +86-18627785180 |
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https://www.finetechnology-ind.com/ |
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