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55779-48-1

55779-48-1 Structure

55779-48-1 Structure
IdentificationMore
[Name]

Coelenteramine
[CAS]

55779-48-1
[Synonyms]

2-[(4-HYDROXYPHENYL)METHYL]-6-(4-HYDROXYPHENYL)-8-(PHENYLMETHYL)-IMDAZO[1,2-A]PYRAZIN-3-(7H)-ONE
2-[(4-HYDROXYPHENYL)METHYL]-6-(4-HYDROXYPHENYL)-8-(PHENYLMETHYL)-IMIDAZO [1,2-A] PYRAZIN-3-(7H)-ONE
2-(BETA-NAPHTHYLMETHYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE
2-(BETA-NAPHTHYLMETHYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZINE-3-(7H)-ONE
2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE
2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYL-IMIDAZOL[1,2-A]PYRAZIN-3-(7H)-ONE
3,2-DIHYDRO-2-(P-HYDROXYBENZYL)-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZOLO[1,2-A]PYRAZIN-3-ONE
8-BENZYL-2-(4-HYDROXYBENZYL)-6-(4-HYDROXYPHENYL)IMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE
CLZ-N
CLZN-N
Coelenteramine
COELENTERAZINE
COELENTERAZINE N
COELENTERAZINE, NATIVE
COELENTERAZINE-N, SYNTHETIC
COELENTERAZIN N
H COELENTERATE LUCIFERIN
NATIVE COELENTERATE LUCIFERIN
Coelenterazine luiferin
Luciferin, Preluciferin,
[Molecular Formula]

C26H21N3O3
[MDL Number]

MFCD00467176
[Molecular Weight]

423.46
[MOL File]

55779-48-1.mol
Chemical PropertiesBack Directory
[Appearance]

Yellow Solid
[Melting point ]

176–181 ℃ (decompose)
[Boiling point ]

641.4±65.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

methanol and ethanol: soluble
[form ]

solid
[pka]

9.91±0.15(Predicted)
[color ]

yellow
[Sensitive ]

Moisture & Light Sensitive
[Usage]

A luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dynamic range
[λmax]

429nm
[Biological Applications]

Calciumindicator; detecting luciferase,protease,gene expression,nucleic acids,proteins,stem cells,quantum dot conjugates,superoxide; tracing protein dynamics; as a substrate for luciferase,alka
[InChI]

InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
[InChIKey]

YHIPILPTUVMWQT-UHFFFAOYSA-N
[SMILES]

C12N=C(CC3=CC=C(O)C=C3)C(=O)N1C=C(C1=CC=C(O)C=C1)NC=2CC1=CC=CC=C1
[CAS DataBase Reference]

55779-48-1(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[F ]

10
[HS Code ]

29339900
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

Yellow Solid
[Uses]

Coelenterazine is a luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dynamic range.
[Definition]

ChEBI: An imidazopyrazine that is imidazo[1,2-a]pyrazin-3(7H)-one in which positions 2, 6, and 8 are substituted by 4-hydroxybenzyl, 4-hydroxyphenyl, and benzyl groups, respectively.
[General Description]

Coelenterazine is a luciferin molecule, which is utilized by several luciferases, such as Renilla,?Oplophorus and?Periphylla.
[Biochem/physiol Actions]

Luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465 nm when Ca2+ binds to the complex; used to measure Ca2+ concentration in cells with high sensitivity and large dynamic range.
Spectrum DetailBack Directory
[Spectrum Detail]

Coelenterazine(55779-48-1)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

55779-48-1(sigmaaldrich)
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