| Identification | More | [Name]
Cefmetazole sodium | [CAS]
56796-39-5 | [Synonyms]
CEFMETAZOLE
Cefmetazone
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-
Cefmetazole-Na
CS-1170 sodium salt
Metafar
Sodium cefmetazole
Cefmetazole sodium
Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
(6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt | [EINECS(EC#)]
627-393-7 | [Molecular Formula]
C15H17N7O5S3 | [MDL Number]
MFCD00865068 | [Molecular Weight]
471.53 | [MOL File]
56796-39-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
>130°C (dec.) | [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble50mg/mL | [form ]
powder | [color ]
White to Off-White | [Water Solubility ]
Soluble in water | [Sensitive ]
Hygroscopic | [Usage]
Semi-synthetic antibiotic derived from Cephamycin. Antibacterial | [Merck ]
14,1926 | [Stability:]
Hygroscopic | [InChIKey]
BITQGIOJQWZUPL-PBCQUBLHSA-M | [SMILES]
[Na+].[H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)CSCC#N)OC)C([O-])=O | [CAS DataBase Reference]
56796-39-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS07,GHS08 | [Signal word ]
Danger | [Hazard statements ]
H315-H317-H319-H334-H335 | [Precautionary statements ]
P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R42/43:May cause sensitization by inhalation and skin contact . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
2
| [RTECS ]
XI0372200
| [HS Code ]
2941.90.3000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3 | [Toxicity]
LD50 i.v. in rats: >5000 mg/kg (Masuda) |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Semi-synthetic antibiotic derived from Cephamycin. Antibacterial | [Definition]
ChEBI: An organic sodium salt that is the sodium salt of cefmetazole. | [Brand name]
Zefazone (Pharmacia & Upjohn）. | [Clinical Use]
Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours. | [storage]
4°C, away from moisture and light |
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| Company Name: |
Boen pharm
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| Telephone: |
86 512-62572107 62962707 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19300/0_EN.htm |
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