ChemicalBook--->CAS DataBase List--->57-56-7

57-56-7

57-56-7 Structure

57-56-7 Structure
IdentificationMore
[Name]

Semicarbazide
[CAS]

57-56-7
[Synonyms]

aminourea
Carbamoylhydrazine
hydrazinecarboxamide
SEMICARBAZIDE
SEMICARBAZIDE, BASE
Aminomocovina
amino-ure
Carbamic acid, hydrazide
carbamicacid,hydrazide
carbamoyl-hydrazin
Carbamylhydrazine
Carbazamide
Hydrazine, carbamoyl-
Semikarbazid
Urea, amino-
Carbazinamide
Semicarbazide, 7 wt. %
SEMICARBAZIDE, 6 WT. % ON SILICA GEL
SEMICARBAZIDE 98%MIN
Carbamine diamide
[EINECS(EC#)]

200-339-6
[Molecular Formula]

CH5N3O
[MDL Number]

MFCD00042824
[Molecular Weight]

75.07
[MOL File]

57-56-7.mol
Chemical PropertiesBack Directory
[Description]

Semicarbazide (SM) is a metabolite of the nitrofurane Nitrofurazone (5-nitro-2- furaldehyde-semicarbazone), used as indicator to detect the use of nitrofurazone in food-producing animals
due to their carcinogenic properties the use of nitrofurans is prohibited within the EU in animal breeding (Commission Regulation 37/2010) .
to harmonise the detection of semicarbazide a Minimum Required Performance Limit (MRPL) of 1 µg/kg is set within the EU (Commission Decision 2003/181).
[Melting point ]

96°C
[Boiling point ]

133.71°C (rough estimate)
[density ]

1.286±0.06 g/cm3(Predicted)
[refractive index ]

1.4451 (estimate)
[storage temp. ]

2-8°C, protect from light
[form ]

powder
[pka]

pK1:3.53(+1) (25°C,μ=0.1)
[Appearance]

White to off-white Solid
[InChI]

1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)
[InChIKey]

DUIOPKIIICUYRZ-UHFFFAOYSA-N
[SMILES]

NNC(N)=O
[CAS DataBase Reference]

57-56-7(CAS DataBase Reference)
[NIST Chemistry Reference]

Hydrazinecarboxamide-(57-56-7)
[EPA Substance Registry System]

57-56-7(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H335-H319-H315-H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
[Safety Statements ]

S22:Do not breathe dust .
[WGK Germany ]

3
[TSCA ]

TSCA listed
[Storage Class]

13 - Non Combustible Solids
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Urea-->Hydrazine sulfate-->Sodium cyanate-->Semicarbazide hydrochloride
[Preparation Products]

Hydrocortisone-->4'-Methylacetophenone-->Semicarbazide hydrochloride-->CIVETONE-->Xanthine-->Nitrofurantoin-->Menthone-->Muscone-->Mitoguazone-->4-Phenylurazole-->ACETONE SEMICARBAZONE
Hazard InformationBack Directory
[Uses]

Semicarbazide is used as a potent nucleophile; forms many crystalline carbonyl derivatives.
[Definition]

ChEBI: A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine.
[Toxicology]

Limited toxicological data are available for semicarbazide. It belongs, however, to a family of chemicals (hydrazines) which are known to cause cancer in animals. Semicarbazide is weakly genotoxic in some in vitro tests. The limited in vivo experimental data available are insufficient to assess whether the activity observed in vitro is also expressed in vivo. Semicarbazide appears to be only a weak carcinogen.
[Precautions]

Semicarbazide is a reactive nucleophile with significant ability to bind to various enzymes; exercise reasonable caution.
Spectrum DetailBack Directory
[Spectrum Detail]

Semicarbazide(57-56-7)1HNMR
Semicarbazide(57-56-7)IR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

57-56-7(sigmaaldrich)
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