| Identification | Back Directory | [Name]
4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride | [CAS]
24735-18-0 | [Synonyms]
SCM-198 HCl
SCM-198 hydrochloride
Leonurin monohydrochloride
4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride
4-Hydroxy-3,5-dimethoxybenzoic acid 4-[(aminoiminomethyl)amino]butyl ester monohydrochloride | [Molecular Formula]
C14H22ClN3O5 | [MDL Number]
MFCD09953249 | [MOL File]
24735-18-0.mol | [Molecular Weight]
347.795 |
| Chemical Properties | Back Directory | [Melting point ]
194℃ | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Very Slightly, Heated) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, easily soluble in methanol and water, derived from Leonurus artemisia (Laur.) SY Hu F. | [Uses]
Leonurine Hydrochloride is an alkaloid plant extract used in the treatment of uterine disorders. Used in the modification of uterine contractions in rats. | [in vivo]
Leonurine (10 mg/kg/d, p.o.) significantly increases the expressions of PPARγ, LXRα, ABCA1 and ABCG1, and decreases both TG and TC levels in serum of mice[1]. Leonurine hydrochloride (50, 100, 200 mg/kg) improves intracellular lipid accumulation via activating AMPK/SREBP1 pathway, enhances biochemical parameters, reduces hepatic lipoperoxide and increases antioxidant levels in mice[2]. Leonurine (20 mg/kg, p.o.) ameliorates osteoarthritis development in mouse DMM model[3]. |
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