ChemicalBook--->CAS DataBase List--->59-32-5

59-32-5

59-32-5 Structure

59-32-5 Structure
IdentificationBack Directory
[Name]

Chloropyramine
[CAS]

59-32-5
[Synonyms]

Synpen
Synopen
Avapena
Allergan
synopenr
Synopen R
Suprastin
allergans
Allergan S
Anaphylline
Halopyramine
Chlorpyramine
CHLOROPYRAMINE
Chlorneoantergan
Chloroneoantergan
Chloropyribenzamine
CHLOROPYRAMINE BASE
Chloropyramine USP/EP/BP
p-Chlorbenzyl-alpha-pyridyl-dimethyl-aethylendiamin
2-[(4-chlorobenzyl)[2-(dimethylamino)ethyl]amino]pyridine
2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-pyridin
2-((p-Chlorobenzyl)(2-(dimethylamino)ethyl)amino)pyridine
Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-
n-(p-chlorobenzyl)-n’,n’-dimethyl-n-(2-pyridyl)-ethylenediamin
n-(p-chlorobenzyl)-n',n'-dimethyl-n-(2-pyridyl)ethylenediamine
Ethylenediamine, N-(p-chlorobenzyl)-N',N'-dimethyl-N-(2-pyridyl)-
n-((4-chlorophenyl)methyl)-n’,n’-dimethyl-n-2-pyridinyl-2-ethanediamine
N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
1,2-Ethanediamine, N-[(4-chlorophenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
1,2-Ethanediamine, N1-[(4-chlorophenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-
[EINECS(EC#)]

200-421-1
[Molecular Formula]

C16H20ClN3
[MDL Number]

MFCD00065266
[MOL File]

59-32-5.mol
[Molecular Weight]

289.8
Chemical PropertiesBack Directory
[Melting point ]

25°C
[Boiling point ]

bp0.2 154-155°
[density ]

1.1031 (rough estimate)
[refractive index ]

1.6010 (estimate)
[pka]

9.00±0.28(Predicted)
[NIST Chemistry Reference]

Chloropyramine(59-32-5)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis, contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms of this drug are suprastin, chlortripelenamine, and synopen.
[Definition]

ChEBI: N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine is an aminopyridine.
[Synthesis]

Chloropyramine, N-(4-chlorobenzyl)-N??,N??-dimethyl-N-2-pyridylethylenediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group.

Synthesis_59-32-5

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