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59703-84-3

59703-84-3 Structure

59703-84-3 Structure
IdentificationMore
[Name]

Piperacillin sodium salt
[CAS]

59703-84-3
[Synonyms]

[2s-[2alpha,5alpha,6beta(s*)]]-6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt
PIPERACILLIN NA
PIPERACILLIN SODIUM
PIPERACILLIN SODIUM SALT
(2s-(2-alpha,5-alpha,6-beta(s*)))-msal
3-dimethyl-7-oxo--piperazinyl)carbonyl)amino)phenylacetyl)amino)-monosodiu
4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(((((4-ethyl-2,3-dioxo-1
cl227193
pentcillin
pipril
sodiumpiperacillin
t1220
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]-
Piperacillin sodium sterile
PIPERACILLIN SODIUM IMP. E (EP): 1-ETHYLPIPERAZINE-2,3-DIONE MM(CRM STANDARD)
PIPERACILLIN SODIUM IMP. H (EP): 6-AMINOPENICILLANIC ACID MM(CRM STANDARD)
PIPERACILLIN SODIUM MM(CRM STANDARD)
PEPERACILLIN SODIUM
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-(9CI)
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2a,5a,6b(S*)]]-
[EINECS(EC#)]

261-868-6
[Molecular Formula]

C23H26N5NaO7S
[MDL Number]

MFCD00917471
[Molecular Weight]

539.54
[MOL File]

59703-84-3.mol
Chemical PropertiesBack Directory
[Appearance]

White to off-white crystalline powder
[Melting point ]

183-185 C (dec.)
[Boiling point ]

793℃
[refractive index ]

180 ° (C=0.8, H2O)
[storage temp. ]

Store at 0-5°C
[solubility ]

H2O: 50 mg/mL, clear, colorless to faintly yellow
[form ]

neat
[color ]

White to Almost white
[Water Solubility ]

Soluble in ethanol, water and methanol.
[Merck ]

7463
[BRN ]

5373920
[Stability:]

Hygroscopic
[InChIKey]

WCMIIGXFCMNQDS-IDYPWDAWSA-M
[SMILES]

[C@H]12SC(C)(C)[C@H](C([O-])=O)N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)C1C=CC=CC=1.[Na+] |&1:0,5,12,16,r|
[CAS DataBase Reference]

59703-84-3(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Warning
[Hazard statements ]

H317-H334
[Precautionary statements ]

P261-P280g-P284-P304+P340-P342+P311a-P501a
[Hazard Codes ]

Xn
[Risk Statements ]

R42/43:May cause sensitization by inhalation and skin contact .
[Safety Statements ]

S22:Do not breathe dust .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[WGK Germany ]

2
[RTECS ]

XI0180000
[HS Code ]

29411099
[Toxicity]

LD50 in mice, rats, dogs, monkeys (g/kg): 5, 2.7, >6, >4 i.v. (Takai)
Hazard InformationBack Directory
[Description]

Piperacillin was synthesized by Toyama Chemicals Company in 1976by acylation of the amino residue of ampicillin. It shows excellent activity against a wide range of grampositive and gram-negative bacteria and has been used as the most potent semisynthetic penicillin. Piperacillin is administered intravenously or intramuscularly for therapy of sepsis, meningitis, respiratory and urinary tract infections, and for abdominal infections caused by Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, Serratia marcescens, Pseudomonas aeruginosa, Proteus, Enterobacter, Citrobacter, and Bacteroides.
[Chemical Properties]

White to off-white crystalline powder
[Uses]

An antibiotic related to penicillin
[Uses]

Penicillin antibacterial.
[Definition]

ChEBI: Piperacillin sodium is an organic sodium salt. It contains a piperacillin(1-).
[Brand name]

Pipracil (Wyeth).
[Synthesis]

is typically prepared from palladium(II) chloride. Step 1: Preparation of Li₂PdCl₄ solution: Stir palladium chloride, lithium chloride and ethanol overnight under nitrogen protection, then filter. Step 2: Preparation of Tris(dibenzylideneacetone)dipalladi
[storage]

Store at 2-8°C, sealed storage, away from moisture
Questions And AnswerBack Directory
[Brand Name(s) in US]

Pipracil
Spectrum DetailBack Directory
[Spectrum Detail]

Piperacillin sodium salt(59703-84-3)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

59703-84-3(sigmaaldrich)
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