| Identification | More | [Name]
Ethyl nicotinoate | [CAS]
614-18-6 | [Synonyms]
3-PYRIDINECARBOXYLIC ACID ETHYL ESTER
ETHYL 3-PYRIDINECARBOXYLATE
ETHYL NICOTINATE
ethyl nicotinoate
ETHYL PYRIDINE-3-CARBOXYLATE
NICOTINIC ACID ETHYL ESTER
RARECHEM AL BI 0185
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
Apamid
Ba 2673
beta-Pyridinecarboxylic acid ethyl ester
Ignicut
Ignocut
Mucotherm
Nicaethan
Nikethan
Nikithan
pyridine-3-carboxylicacidethylester
Ethylnicotinate,99% | [EINECS(EC#)]
210-370-7 | [Molecular Formula]
C8H9NO2 | [MDL Number]
MFCD00006389 | [Molecular Weight]
151.16 | [MOL File]
614-18-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colourless to yellow liquid | [Melting point ]
8-10 °C (lit.) | [Boiling point ]
223-224 °C (lit.) | [density ]
1.107 g/mL at 25 °C(lit.)
| [vapor pressure ]
4.2-5.5Pa at 20-25℃ | [refractive index ]
n20/D 1.504(lit.)
| [Fp ]
93 °C
| [storage temp. ]
2-8°C
| [solubility ]
50g/l | [form ]
neat | [pka]
pK1:3.35(+1) (25°C) | [color ]
light yellow
| [Specific Gravity]
1.107 | [Water Solubility ]
miscible | [Detection Methods]
GC | [BRN ]
122937 | [Cosmetics Ingredients Functions]
SKIN CONDITIONING
PERFUMING | [InChI]
1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3 | [InChIKey]
XBLVHTDFJBKJLG-UHFFFAOYSA-N | [SMILES]
CCOC(=O)c1cccnc1 | [LogP]
1.32 | [Surface tension]
72mN/m at 1g/L and 20℃ | [CAS DataBase Reference]
614-18-6(CAS DataBase Reference) | [NIST Chemistry Reference]
3-Pyridinecarboxylic acid, ethyl ester(614-18-6) | [Storage Precautions]
Air sensitive;Light sensitive | [EPA Substance Registry System]
614-18-6(EPA Substance) |
| Questions And Answer | Back Directory | [Preparation]
Nicotinic acid, anhydrous ethanol, and a solid acid catalyst for esterification are added to toluene. The mixture is stirred at 50–65°C for 3–6 hours, then heated and refluxed to separate water. Once no water is discharged, the reaction is complete. The mixture is cooled to room temperature, filtered, and the solid acid catalyst for esterification is recovered. Toluene is recovered from the filtrate under reduced pressure. The resulting light yellow transparent liquid is ethyl nicotinate. The molar ratio of nicotinic acid to anhydrous ethanol is 1:1–1:2, the weight ratio of nicotinic acid to toluene is 1:0.3–1:8, and the amount of solid acid catalyst added is 0.01–0.1 times the weight of nicotinic acid. The solid acid catalyst for esterification is HND230 solid catalyst. |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H314-H335 | [Precautionary statements ]
P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/38:Irritating to eyes and skin .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
8-9-23 | [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29333999 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B
STOT SE 3 | [Toxicity]
LD50 orally in Rabbit: > 2005 mg/kg |
| Hazard Information | Back Directory | [Description]
Ethyl nicotinate(614-18-6) is a chemical attractant used to prevent and control plant pests. Ethyl nicotinate was found to be a potent attractant forThrips obscuratus in peaches and apricots. It is more attractive than ripe fruit and catches peak at harvest. Long season trapping demonstrated the efficiency of chemical traps compared to unbaited traps. The attractiveness of the chemical was maintained for at least 2 weeks when 50 μl of the chemical was placed in an open 2 ml vial cap. Various pyralids, geometrids (Lepidoptera), and chironomids (Diptera) were also attracted in low numbers to ethyl nicotinate[1].
| [Chemical Properties]
clear colourless to yellow liquid | [Uses]
Ethyl nicotinate(614-18-6) is a nicotinic acid derivative used for skin-conditioning cosmetics.
| [Definition]
ChEBI:Ethyl nicotinate is a member of pyridines and an aromatic carboxylic acid. | [Solubility in water]
Soluble in water (50 mg/ml at 20° C). | [References]
[1] D R PENMAN. Ethyl nicotinate?: A chemical attractant forThrips obscuratus (Thysanoptera: Thripidae) in stonefruit in New Zealand.[J]. Journal of Chemical Ecology, 1982. DOI:10.1007/BF00987763. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|