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62-38-4

62-38-4 Structure

62-38-4 Structure
IdentificationMore
[Name]

PHENYLMERCURIC ACETATE
[CAS]

62-38-4
[Synonyms]

(ACETATO)PHENYL MERCURY
(ACETOXYMERCURI)BENZENE
ACETOXYPHENYLMERCURY
GALLOTOX(R)
LABOTEST-BB LT00085754
LIQUIPHENE(R)
MERCURI PHENYL ACETATE
MERCURY PHENYL ACETATE
METASOL 30(R)
NYLMERATE(R)
PHENYLMERCURIC ACETATE
PHENYLMERCURY(+2)ACETATE
PHENYLMERCURY ACETATE
PHENYLMERCURY(II) ACETATE
PHIX(R)
PMA
PM ACETATE
PMAC(R)
PMA(R)
PMAS(R)
[EINECS(EC#)]

200-532-5
[Molecular Formula]

C8H8HgO2
[MDL Number]

MFCD00008691
[Molecular Weight]

336.74
[MOL File]

62-38-4.mol
Chemical PropertiesBack Directory
[Appearance]

Phenylmercury acetate is a white or yellow crystalline solid.
[Melting point ]

148-151 °C(lit.)
[density ]

2,4 g/cm3
[storage temp. ]

APPROX 4°C
[solubility ]

Slightly soluble in water, soluble in acetone and in alcohol.
[form ]

Powder
[color ]

white
[Specific Gravity]

2.4
[Odor]

Acetic acid odor
[Stability:]

Stable. Incompatible with strong oxidizing agents.
[Water Solubility ]

Soluble in alcohol, benzene and glacial acetic acid. Slightly soluble in water.
[Merck ]

14,7300
[CAS DataBase Reference]

62-38-4(CAS DataBase Reference)
[EPA Substance Registry System]

Phenylmercury acetate (62-38-4)
Safety DataBack Directory
[Hazard Codes ]

T,N
[Risk Statements ]

R25:Toxic if swallowed.
R34:Causes burns.
R48/24/25:Toxic: danger of serious damage to health by prolonged exposure in contact with skin and if swallowed .
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[Safety Statements ]

S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S37:Wear suitable gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
[RIDADR ]

UN 1674 6.1/PG 2
[WGK Germany ]

3
[RTECS ]

OV6475000
[F ]

8
[TSCA ]

Yes
[HazardClass ]

6.1
[PackingGroup ]

II
[HS Code ]

28521000
[Safety Profile]

Poison by ingestion, intravenous, intraperitoneal, subcutaneous, and possibly other routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. See also MERCURY COMPOUNDS. When heated to decomposition it emits toxic fumes of Hg.
[Hazardous Substances Data]

62-38-4(Hazardous Substances Data)
[Toxicity]

LD50 oral in rat: 41mg/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium hydroxide-->Acetic acid-->Nitric acid-->Benzene-->Mercury-->Mercuric Oxide
[Preparation Products]

pressure sensitive adhesive J-686 series-->PHENYLMERCURIC NITRATE
Hazard InformationBack Directory
[General Description]

Small lustrous prisms. Toxic by ingestion, inhalation and skin absorption. May severely irritate skin and eyes. Used as an herbicide and fungicide. as such, is mixed with organic solvent for the purpose of application.
[Reactivity Profile]

PHENYLMERCURIC ACETATE may react with strong oxidizing agents .
[Health Hazard]

Extremely toxic. The probable oral lethal dose for humans is 5-50 mg/kg, between 7 drops and 1 teaspoonful for a 70 kg (150 lb.) person.
[Potential Exposure]

Phenylmercury acetate is used as an antiseptic, fungicide; for fungal and bacterial control; herbicide and control of crabgrass; mildewcide for paints; slimicide in paper mills. It was also used in contraceptive gels and foams.
[Fire Hazard]

Fire may produce irritating or poisonous gases. When heated to decomposition, very toxic mercuric fumes may be given off. Phenylmercuric ion is incompatible with halides, with which precipitates are formed.
[First aid]

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Keep victim quiet and maintain normal body temperature. Effects may be delayed; keep victim under observation.
Antidotes and Special Procedures for medical personnel: The drug NAP (n-acetyl penicillamine) has been used to treat mercury poisoning, with mixed success.
[Shipping]

UN1674 Phenylmercuric acetate, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
[Incompatibilities]

A strong reducing agent. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, halogens.
[Chemical Properties]

Phenylmercuric acetate occurs as a white to creamy white, odorless or almost odorless, crystalline powder or as small white prisms or leaflets.
[Chemical Properties]

Phenylmercury acetate is a white or yellow crystalline solid.
[Chemical Properties]

white crystalline powder
[Waste Disposal]

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. React to produce soluble nitrate form, precipitate as mercuric sulfide. Return to supplier.
[Uses]

antiulcer
[Uses]

Herbicide; fungicide.
[Uses]

Phenylmercuric acetate is used as catalyst; fungicide; herbicide; algicide; preservative in antibiotic eye drops, eye cosmetics, shampoos, etc.
[Definition]

ChEBI: Phenylmercury acetate is an arylmercury compound and a member of benzenes.
[Production Methods]

Phenylmercuric acetate is readily formed by heating benzene with mercuric acetate.
[Pharmaceutical Applications]

Phenylmercuric acetate is used as an alternative antimicrobial preservative to phenylmercuric borate or phenylmercuric nitrate in a limited range of cosmetics (in concentrations not exceeding 0.007% of mercury calculated as the metal) and pharmaceuticals. It may be used in preference to phenylmercuric nitrate owing to its greater solubility.
Phenylmercuric acetate is also used as a spermicide;
[Safety]

Phenylmercuric acetate is mainly used as an antimicrobial preservative in topical pharmaceutical formulations. A number of adverse reactions to mercury-containing preservatives have been reported; see Phenylmercuric Nitrate.
LD50 (chicken, oral): 60 mg/kg
LD50 (mouse, IP): 13 mg/kg
LD50 (mouse, IV): 18 mg/kg
LD50 (mouse, oral): 13 mg/kg
LD50 (mouse, SC): 12 mg/kg
LD50 (rat, oral): 41 mg/kg
[Environmental Fate]

If released into air, soil, or water, phenylmercuric acetate is unlikely to volatilize and is instead expected to be bound to particulates based on a low vapor pressure (6 × 10-6 mm Hg) and low Henry’s constant (5.66 × 10-10 atmm3 mol -1). Photolysis has the potential to degrade phenylmercuric acetate, releasing inorganic mercury which can volatilize and enter the atmosphere from superficial soils or water. If released into soil, the mobility of parent phenylmercuric acetic acid is expected to be high based on a Koc of 60. Water releases would result in quick dispersion since water solubility is high (4370 mg l-1). Once in solution, especially with harder water, it will dissociate into a salt. The cation will adsorb to particulates or humics suspended in the water column or in sediment, with little bioconcentration in aquatic species.
[storage]

As for other phenylmercuric salts; see Phenylmercuric Nitrate.
Phenylmercuric acetate should be stored in a well-closed container, protected from light, in a cool, dry place.
[Purification Methods]

It forms small colourless lustrous prisms from EtOH. Its solubility in H2O is 0.17%, but it is more soluble in EtOH, Me2CO and *C6H6. [Maynard J Am Chem Soc 46 1510 1925, Coleman et al. J Am Chem Soc 59 2703 1937, J Am Pharm Assoc 25 752 1936, Beilstein 16 IV 1720.] See PhHgOH below.
[Toxicity evaluation]

Toxic effects of phenylmercuric acetate are correlated with its rapid metabolic breakdown into the mercuric ion. Generally, mercury interferes with cellular enzymatic mechanisms by combining with sulfhydryl (–SH) groups of different enzymes and thereby produces nonspecific cell injury or death.
[Regulatory Status]

Included in the FDA Inactive Ingredients Database (ophthalmic ointments; topical emulsions/creams; vaginal emulsions/creams). Included in the Canadian List of Acceptable Non-medicinal Ingredients (ophthalmic, nasal and otic preparations up to 0.004%; there must be no other suitable alternative preservative available).
Phenylmercuric acetate is no longer permitted to be used as a pesticide in the USA. Its use in cosmetic products in the USA is limited to eye area cosmetics at not more than 0.0065% provided that there is no other suitable available preservative. It is specifically prohibited in vaginal contraceptive drug products and antimicrobial diaper rash drug products in the USA. Phenylmercuric compounds are prohibited from use in cosmetic products in Canada.
In Europe, use in cosmetic products is limited to eye makeup and eye makeup remover at concentrations not exceeding 0.007% mercury alone or in combination with other permitted mercurial compounds.In France, a maximum concentration of 0.01% is permitted for use in pharmaceuticals. The use of mercurial compounds in cosmetics in Japan is limited to concentrated shampoo or cream at not more than 0.003% Hg and eye makeup at not more than 0.0065% Hg.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

phenyl mercuric acetate(62-38-4).msds
Spectrum DetailBack Directory
[Spectrum Detail]

PHENYLMERCURIC ACETATE(62-38-4)1HNMR
PHENYLMERCURIC ACETATE(62-38-4)IR1
PHENYLMERCURIC ACETATE(62-38-4)IR2
PHENYLMERCURIC ACETATE(62-38-4)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Phenylmercuricacetate,98%(62-38-4)
[Alfa Aesar]

Phenylmercury acetate, 98%(62-38-4)
[Sigma Aldrich]

62-38-4(sigmaaldrich)
62-38-4 suppliers list
Tags:62-38-4 Related Product Information
62-38-4 1600-27-7 7439-97-6 6283-24-5