| Identification | More | [Name]
1,1,3,3-Tetramethylurea | [CAS]
632-22-4 | [Synonyms]
1,1,3,3-TETRAMETHYLUREA
N,N,N',N'-TETRAMETHYLUREA
TETRAMETHYLUREA
TMU
((CH3)2N)2CO
1,1,3,3-tetramethyl-ure
Temur
Tetramethylharnstoff
tetramethyl-ure
Tetramethyluree
Urea, 1,1,3,3-tetramethyl-
urea,1,1,3,3-tetramethyl-
1,1,3,3-Tetramethylurea Tetramethylurea Temur
1,1,3,3-Tetramethylurea, nonaqueous titration grade, 99+%
Urea, tetramethyl-
TERAMETHYLUREA
1,1,3,3-Tetramethylurea, TMU
1,1,3,3-Tetramethylurea, Tetramethylurea, TMU
1,1,3,3-Tetramethylurea, 99+%, nonaqueous titration grade
1,1,3,3-Tetramethylurea, nonaqueous titration grade | [EINECS(EC#)]
211-173-9 | [Molecular Formula]
C5H12N2O | [MDL Number]
MFCD00008319 | [Molecular Weight]
116.16 | [MOL File]
632-22-4.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS LIQUID | [Melting point ]
−1 °C(lit.) | [Boiling point ]
177 °C(lit.) | [density ]
0.968 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.451(lit.)
| [Fp ]
150 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
H2O: 1 M at 20 °C, miscible
| [form ]
Liquid | [pka]
2.0(at 25℃) | [color ]
Clear colorless to pale yellow | [Odor]
faint pleasant odor | [PH]
5-8 (25℃, 1M in H2O) | [Relative polarity]
5 | [Water Solubility ]
miscible | [Usage]
1) As intermediates in pesticides. 2) As a high-grade solvent, in dyestuff and other industries. 3) As intermediates in surfactant. 4) In peptides and other products produced by the bio-chemical industry. | [Merck ]
14,9230 | [BRN ]
773898 | [Dielectric constant]
24.460000000000001 | [InChIKey]
AVQQQNCBBIEMEU-UHFFFAOYSA-N | [CAS DataBase Reference]
632-22-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Urea, tetramethyl-(632-22-4) | [EPA Substance Registry System]
632-22-4(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS05,GHS07,GHS08 | [Signal word ]
Danger | [Hazard statements ]
H302-H315-H318-H360D | [Precautionary statements ]
P202-P280-P301+P312-P302+P352-P305+P351+P338-P308+P313 | [Hazard Codes ]
Xn,T | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S53:Avoid exposure-obtain special instruction before use .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
NA 1993 / PGIII | [WGK Germany ]
3 | [RTECS ]
YU2625000 | [F ]
3-10 | [TSCA ]
Yes | [HazardClass ]
CBL | [HS Code ]
29241900 | [Safety Profile]
Moderately toxic by ingestion and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. Combustible when exposed to heat, flame, and oxidizers. To fight fire, use foam, mist, spray, dry chemicals. When heated to decomposition it emits toxic fumes of NOx. | [Hazardous Substances Data]
632-22-4(Hazardous Substances Data) | [Toxicity]
LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen) |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to pale yellow liquid | [Uses]
1) As intermediates in pesticides. 2) As a high-grade solvent, in dyestuff and other industries. 3) As intermediates in surfactant. 4) In peptides and other products produced by the bio-chemical industry. | [Uses]
As solvent and reagent. | [Uses]
Tetramethylurea is an excellent solvent for organic substances, in particular aromatic compounds. | [Definition]
ChEBI: A member of the class of ureas that is urea substituted by methyl groups at positions 1, 1, 3 and 3 respectively. Metabolite observed in cancer metabolism. | [Preparation]
The reaction of dimethylamine with phosgene in the presence of e. g. 50 % sodium hydroxide solution and subsequent extraction with 1,2-dichloroethane yields tetramethylurea in 95% yield. | [Purification Methods]
Dry it over BaO and distil it under nitrogen. It denatures proteins in H2O. [Elbaum & Herskovits Biochemistry 13 1268 1974, Kane Anal Biochem 53 350 1973, Beilstein 4 IV 225.] | [Toxics Screening Level]
The initial threshold screening level (ITSL) for tetramethylurea is 0.8 μg/m3 based on an annual averaging time and 230 μg/m3 based on a 24-hour averaging time. |
| Spectrum Detail | Back Directory | [Spectrum Detail]
1,1,3,3-Tetramethylurea(632-22-4)MS
1,1,3,3-Tetramethylurea(632-22-4)1HNMR
1,1,3,3-Tetramethylurea(632-22-4)13CNMR
1,1,3,3-Tetramethylurea(632-22-4)IR1
1,1,3,3-Tetramethylurea(632-22-4)Raman
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|