| Identification | More | [Name]
THIOACETANILIDE | [CAS]
637-53-6 | [Synonyms]
SPECS AQ-012/40221353
THIOACETANILIDE
Acetanilide, thio-
Ethanethioamide,N-phenyl-
n-phenyl-ethanethioamid
N-Phenylethanethioamide
N-Phenylthioacetamide
N-Phenyl-thioacetamide
thio-acetanilid
USAF ek-1902
usafek-1902
Thilacetanilide
Thioacetanilide99%
USAF AK-1902 | [EINECS(EC#)]
211-288-4 | [Molecular Formula]
C8H9NS | [MDL Number]
MFCD00004942 | [Molecular Weight]
151.23 | [MOL File]
637-53-6.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow crystalline powder | [Melting point ]
76-79 °C (lit.) | [Boiling point ]
147 °C / 1mmHg | [density ]
1.1041 (rough estimate) | [refractive index ]
1.5700 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
11.16±0.70(Predicted) | [color ]
White to Gray to Brown | [Cosmetics Ingredients Functions]
BLEACHING
ANTIOXIDANT | [InChI]
1S/C8H9NS/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10) | [InChIKey]
MWCGLTCRJJFXKR-UHFFFAOYSA-N | [SMILES]
CC(=S)Nc1ccccc1 | [LogP]
1.710 | [CAS DataBase Reference]
637-53-6(CAS DataBase Reference) | [EPA Substance Registry System]
Thioacetanilide (637-53-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
AE7350000
| [TSCA ]
TSCA listed | [HS Code ]
29309099 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation |
| Hazard Information | Back Directory | [Chemical Properties]
yellow crystalline powder | [Uses]
Thioacetanilide (N-Phenylthioacetamide) is a thioderivative of acetanilide that exhibits Z/E isomer preference and solvent dependence[1]. | [General Description]
Metabolism and acute toxicity of thioacetanilide has been studied in rat. Thioacetanilide undergoes nucleophilic addition reaction with superoxide ion in dimethyl sulfoxide. | [References]
[1] Song S, et al. Contribution of Solvents to Geometrical Preference in the Z/E Equilibrium of N-Phenylthioacetamide. J Org Chem. 2022 Feb 4;87(3):1641-1660. DOI:10.1021/acs.joc.1c00801 |
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