| Identification | More | [Name]
ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE | [CAS]
64987-03-7 | [Synonyms]
(2-FORMYLAMINOTHIAZOL-4-YL)-OXO-ACETIC ACID ETHYL ESTER
ETHYL 2-(2-FORMAMIDO-1,3-THIAZOL-4-YL)-2-OXO-ACETATE
ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE
ETHYL-2-(2-FORMYLAMINO-4-THIAZOLE-4-YL)-1-OXY ACETATE
ETHYL 2-(2-FORMYLAMINOTHIAZOL-4-YL) GLYOXYLATE
ETHYL 2-(FORMYLAMINO)-4-THIAZOLEGLYOXYLATE
LABOTEST-BB LT00441209
ethyl 2-formamido-alpha-oxothiazol-4-acetate
Ethyl-2-(2-Formylamino-4-Thiazole-4-Yl)-1-Oxo-Acetate
ETHYL 2-(FORMYLAMINO)THIAZOL-4-YLGLYOXYLATE
ethyl 2-(formylamino)-4-thiazoleglyoxalate
2-(Formylamino)-α-oxo-4-thiazoleacetic acid ethyl ester
2-[2-(Formylamino)-4-thiazolyl]-2-oxoacetic acid ethyl ester | [EINECS(EC#)]
265-299-4 | [Molecular Formula]
C8H8N2O4S | [MDL Number]
MFCD00010412 | [Molecular Weight]
228.23 | [MOL File]
64987-03-7.mol |
| Chemical Properties | Back Directory | [Appearance]
light yellow powder | [Melting point ]
232-234 °C | [Boiling point ]
381.3±34.0 °C(Predicted) | [density ]
1.5150 (rough estimate) | [refractive index ]
1.5690 (estimate) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly, Heated), DMSO (Slightly) | [form ]
Solid | [pka]
8.11±0.70(Predicted) | [color ]
Light Yellow | [CAS DataBase Reference]
64987-03-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [REACH Registrations]
Active | [HS Code ]
29341000 |
| Hazard Information | Back Directory | [Chemical Properties]
light yellow powder | [Uses]
Ethyl 2-(2-Formamidothiazol-4-yl)-2-oxoacetate is an intermediate formed in the synthesis of Cefixime Ethyl Ester Sodium Salt (C242830), an ester impurity of the third generation cephalosporin antibiotic, Cefixime (C242800). | [Synthesis]
A mixture of ethylene acetate tetrahydrate (120 g), acetic acid (1000 ml) and acetic anhydride (100 ml) was stirred in an oil bath heated to 130°C to 135°C for 20 minutes and potassium permanganate (20 g) was added to the mixture over a period of 5 minute |
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