| Identification | More | [Name]
2'-HYDROXY-6'-METHOXYACETOPHENONE | [CAS]
703-23-1 | [Synonyms]
1-(2-HYDROXY-6-METHOXYPHENYL)ETHAN-1-ONE
1-(2-HYDROXY-6-METHOXYPHENYL)ETHANONE
2'-HYDROXY-6'-METHOXYACETOPHENONE
2-HYDROXY-6-METHOXYACETOPHENONE
6'-Hydroxy-2'-methoxyacetophenone
Acetophenone, 2'-hydroxy-6'-methoxy-
2-Acetyl-3-methoxyphenol | [EINECS(EC#)]
211-872-9 | [Molecular Formula]
C9H10O3 | [MDL Number]
MFCD00008732 | [Molecular Weight]
166.17 | [MOL File]
703-23-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Yellow crystalline powder | [Melting point ]
58-60 °C(lit.) | [Boiling point ]
141 °C16 mm Hg(lit.) | [density ]
1.158 | [refractive index ]
1.5500 (estimate) | [Fp ]
141°C/16mm | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
solid | [pka]
9.79±0.10(Predicted) | [color ]
Light yellow to yellow | [BRN ]
1869049 | [LogP]
2.390 (est) | [CAS DataBase Reference]
703-23-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
N | [HS Code ]
29145090 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder | [Uses]
2′-Hydroxy-6′-methoxyacetophenone was used as starting material in the synthesis of 5-methoxyflavaone. It was also used in synthesis of 5,6-dihydroxyflavone. | [Uses]
2''-Hydroxy-6''-methoxyacetophenone is useful in the synthesis of an aminopyrazole compound which is used to treat cancer and inhibits Chk1. 2''-Hydroxy-6''-methoxyacetophenone is also used to prepare 5,?4''-?disubstituted flavones, predicted androgen receptor antagonists and naphthopyrazolyl carbothioamides which are anticancer agents. | [Definition]
ChEBI: 2'-Hydroxy-6'-methoxyacetophenone is an aromatic ketone. | [Preparation]
Preparation by reaction of methyl iodide on 2,6-dihydroxyacetophenone with potassium carbonate in boiling acetone (56%). | [General Description]
An organometallic synthetic route to 2′-hydroxy-6′-methoxyacetophenone was reported. |
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