| Identification | More | [Name]
4'-Methylbiphenyl-2-carboxylic acid | [CAS]
7148-03-0 | [Synonyms]
2-(4-METHYLPHENYL)BENZOIC ACID
2-BIPHENYL-4'-METHYL-CARBOXYLIC ACID
2-(P-TOLYL)BENZOIC ACID
4'-METHYL[1,1'-BIPHENYL]-2-CARBOXYLIC ACID
4'-METHYL-2-BIPHENYLCARBOXYLIC ACID
4'-METHYLBIPHENYL-2-CARBOXYLIC ACID
AKOS BAR-0260
RARECHEM AL BO 0764
1’-biphenyl]-2-carboxylicacid,4’-methyl-[
4'-Methyl-2-carboxybiphenyl
o-Tolylbenzoic acid
2-(4-mehtylphenyl)benzoic acid
4''-METHYLBIPHENYL-2-CARBONYLIC ACID
4''-METHYL-2-BISPHENYLCARBOXYLIC ACID,(HPLC): NLT 98.5%
4''-METHYL-2-BIPENYLCARBOXYLIC ACID
4'-Methyl-2-bipenylcarboxylic acid
[1,1'-Biphenyl]-2-carboxylic acid, 4'-methyl- | [EINECS(EC#)]
230-462-0 | [Molecular Formula]
C14H12O2 | [MDL Number]
MFCD00045826 | [Molecular Weight]
212.24 | [MOL File]
7148-03-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
146-148°C | [Boiling point ]
354.5±11.0 °C(Predicted) | [density ]
1.156±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO, Methanol | [form ]
Solid | [pka]
3.90±0.36(Predicted) | [color ]
White | [InChI]
InChI=1S/C14H12O2/c1-10-6-8-11(9-7-10)12-4-2-3-5-13(12)14(15)16/h2-9H,1H3,(H,15,16) | [InChIKey]
ZSTUEICKYWFYIC-UHFFFAOYSA-N | [SMILES]
C1(C2=CC=C(C)C=C2)=CC=CC=C1C(O)=O | [CAS DataBase Reference]
7148-03-0(CAS DataBase Reference) | [EPA Substance Registry System]
7148-03-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [TSCA ]
TSCA listed | [HS Code ]
29163990 |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow solid | [Uses]
4’-Methylbiphenyl-2-carboxylic Acid is used in the synthesis of angiotensin II receptor antagonists used as potent orally active antihypertensives. | [General Description]
4′-Methyl-2-biphenylcarboxylic acid (4′-Methyl-bi-phenyl-2-carboxyl-ic acid) can be synthesized by reacting 4′-methylbiphenyl-2-carbonitrile with methanol and 30% NaOH solution. Its crystal structure has been characterized by the centrosymmetric hydrogen-bonded dimers. | [Purification Methods]
Crystallise the acid from toluene or *C6H6 (m 147-148o). [Beilstein 9 H 677, 9 IV 2523.] |
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